Comparative outcomes of the left atrial appendage Isolation and Preservation groups
| Adverse clinical outcomes | Unadjusted | IPTW-adjusted | |||||||
| Early outcomes | Isolation (n=460) | Preservation (n=413) | OR | 95% CI | P value | OR | 95% CI | P value | |
| Event, no. of patients (%) | |||||||||
| Mortality (<30 days) | 5 (1.1) | 6 (1.5) | 0.75 | 0.23 to 2.46 | 0.630 | 1.16 | 0.52 to 2.45 | 0.720 | |
| Stroke | 4 (0.9) | 10 (2.4) | 0.35 | 0.11 to 1.14 | 0.081 | 0.71 | 0.38 to 1.34 | 0.289 | |
| Late outcomes | Event, n (no./100 PY) | Competing event, n | HR/SHR | 95% CI | P value | HR/SHR | 95% CI | P value | |
| Isolation (n=460) | Preservation (n=413) | ||||||||
| Mortality | 67 (2.6) | 67 (2.8) | 0.94 | 0.67 to 1.32 | 0.761 | 0.85 | 0.57 to 1.27 | 0.429 | |
| Stroke | 8 (0.3) | 18 (0.8) | 124 | 0.42 | 0.18 to 0.96 | 0.039 | 0.28 | 0.15 to 0.51 | <0.001 |
| AF recurrence | 123 (6.0) | 128 (6.9) | 88 | 0.89 | 0.70 to 1.14 | 0.354 | 0.92 | 0.78 to 1.08 | 0.291 |
AF, atrial fibrillation; IPTW, inverse-probability of treatment weighting; PY, patient-year; SHR, subdistribution HR.