Univariable and multivariable Cox regression analysis for prediction of secondary endpoints (cardiovascular-related readmission or emergency department visit)
| Univariable Cox regression | Multivariable Cox regression | |||||
| Variable | Patients with secondary endpoint n=60 | Patients without secondary endpoints n=1324 | HR (95% CI) | P value | HR (95% CI) | P value |
| Age, years | 62.1±13 | 63.7±14 | 1.00 (0.98 to 1.02) | 0.98 | 1.01 (0.66 to 1.03) | 0.64 |
| Male, n (%) | 34 (56.7%) | 680 (51.4) | 0.79 (0.48 to 1.33) | 0.39 | 0.84 (0.49 to 1.43) | 0.53 |
| Diabetes, n (%) | 11 (18.3) | 240 (18.1) | 1.05 (0.54 to 2.01) | 0.89 | 1.19 (0.59 to 2.41) | 0.62 |
| Hypertension, n (%) | 28 (476%) | 712 (53.8) | 0.75 (0.45 to 1.25) | 0.27 | 0.66 (0.35 to 1.23) | 0.19 |
| Dyslipidaemia, n (%) | 26 (43.3) | 614 (46.4) | 0.89 (0.53 to 1.48) | 0.65 | 0.91 (0.48 to 1.71) | 0.77 |
| Smoking, n (%) | 10 (16.7) | 226 (17.1) | 0.93 (0.49 to 1.91) | 0.92 | 0.98 (0.49 to 1.99) | 0.97 |
| Family history of CAD, n (%) | 13 (21.7) | 357 (27) | 0.76 (0.41 to 1.39) | 0.73 | 0.77 (0.42 to 1.44) | 0.41 |
| History CAD, n (%) | 10 (16.7) | 174 (13.1) | 1.34 (0.68 to 2.64) | 0.39 | 1.52 (0.71 to 3.24) | 0.28 |
| HEART score=0, n (%) | 5 (6.6) | 97 (7.3) | 78 (0.56 to 1.48) | 0.62 | 0.81 (0.57 to 1.34) | 0.53 |
| HEART score=1, n (%) | 22 (36.7) | 454 (34.4) | 1.02 (0.73 to 1.56) | 0.34 | 1.01 (0.64 to 1.63) | 0.32 |
| HEART score=2, n (%) | 18 (30) | 502 (37.8) | 0.89 (0.34 to 2.01) | 0.53 | 0.92 (0.41 to 1.99) | 0.56 |
| HEART score=3, n (%) | 15 (26.7) | 271 (20.5) | 0.95 (0.34 to 2.02) | 0.61 | 0.89 (0.44 to 1.87) | 0.47 |
| ECG changes, n (%) | 6 (10) | 89 (6.7) | 1.63 (0.70 to 3.80) | 0.25 | 1.55 (0.67 to 3.63) | 0.30 |
| HTN responses, n (%) | 5 (8.3%) | 105 (8) | 1.01 (0.41 to 2.52) | 0.98 | 1.03 (0.46 to 2.44) | 0.75 |
| Positive NISI, n (%) | 6 (10) | 62 (4.7) | 3.07(1.32 to 7.15) | 0.009 | 3.06 (1.31 to 7.14) | 0.01 |
CAD, coronary artery disease; NISI, non-invasive stress imaging.