Table 5

Independent associations of changes in body composition measures and incident HF from baseline to imaging visit (mean 10 years from baseline visit) in analyses restricted to subset of participants with repeat body composition measures (57 670 participants) and without interval HF event before the imaging visit*

Body composition⊿ % < –8% in body composition−8% ≤ ⊿ % < –2% in body compositionStable body composition –2% ≤ % change <2%≥ 2% ⊿ %< 10% in body composition≥ 10% ⊿ in body composition
HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)
Anthropometry
 Body mass index1.35 (1.02 to 1.79)1.07 (0.89 to 1.29)1.00 (0.82 to 1.22)0.87 (0.70 to 1.09)1.96 (1.36 to 2.82)
 Waist circumference1.07 (0.81 to 1.41)1.06 (0.871.29)1.00 (0.79 to 1.27)1.15 (0.96 to 1.39)1.23 (0.89 to 1.71)
 Waist-to-hip ratio1.40 (0.96 to 2.05)1.07 (.87 to 1.33)1.00 (0.81 to 1.23)1.19 (1.00 to 1.40)1.04 (0.72 to 1.50)
Bioimpedance
 Body fat mass1.10 (0.90 to 1.34)1.33 (1.04 to 1.70)1.00 (0.72 to 1.38)0.96 (0.75 to 1.22)0.89 (0.73 to 1.09)
 Body fat-free mass1.07 (0.77 to 1.50)1.12 (0.96 to 1.30)1.00 (0.82 to 1.23)1.42 (1.08 to 1.87)4.26 (2.12 to 8.55)
  • *HR estimates are floated absolute risks of HF and models were stratified by age at risk (in 5-year ranges), sex and UK region and adjusted for ethnicity, education, social deprivation, smoking, alcohol and physical activity.

  • HF, heart failure.