Table 4

HR (95% CI) for HF per five usual BMI units equivalent higher usual body composition measures with adjustment for potential intermediate risk factors

ModelsModel 1Model 2Model 3Model 4
HR (95% CI)χ2HR (95% CI)χ2HR (95% CI)χ2HR (95% CI)χ2
Usual levels of anthropometry
 Body mass index1.57 (1.54 to 1.60)19941.48 (1.45 to 1.52)10171.37 (1.33 to 1.40)5991.11 (1.02 to 1.20)399
 Waist circumference1.67 (1.64 to 1.71)19921.57 (1.52 to 1.61)10141.43 (1.39 to 1.48)6201.36 (1.33 to 1.41)426
 Waist-to-hip ratio1.67 (1.62 to 1.73)10831.49 (1.43 to 1.54)4511.38 (1.33 to 1.44)2991.32 (1.27 to 1.37)207
Usual levels of bioimpedance measures
 Body fat mass1.55 (1.52 to 1.58)17001.46 (1.42 to 1.49)8721.34 (1.30 to 1.37)4881.27 (1.24 to 1.31)304
 Body fat-free mass1.25 (1.23 to 1.27)8741.19 (1.17 to 1.21)4131.15 (1.13 to 1.17)2511.13 (1.11 to 1.15)209
Usual levels of DXA imaging measures
 Visceral fat1.25 (1.16 to 1.35)331.18 (1.08 to 1.30)131.15 (1.05 to 1.26)81.12 (1.02 to 1.23)5
 Subcutaneous fat1.44 (1.26 to 1.65)281.29 (1.10 to 1.51)101.22 (1.04 to 1.43)61.15 (0.98 to 1.36)3
 Body fat mass1.44 (1.28 to 1.62)361.30 (1.13 to 1.50)131.23 (1.06 to 1.43)81.17 (1.00 to 1.36)4
 Body fat-free mass1.26 (1.14 to 1.38)221.19 (1.07 to 1.33)101.17 (1.05 to 1.30)81.15 (1.03 to 1.28)7
  • Model 1: stratified by age at risk (5-year age groups), sex and UK region and adjusted for ethnicity, education, social deprivation, smoking, alcohol and physical activity.

  • Model 2: model 1+systolic blood pressure, glycated haemoglobin, blood glucose, diabetes, low density lipoprotein cholesterol and high density lipoprotein cholesterol.

  • Model 3: model 2+estimated glomerular filtration rate.

  • Model 4: model 3+C reactive protein.

  • BMI, body mass index; DXA, dual X-ray absprtiometry; HbA1c, glycated haemoglobin; HF, heart failure.