Table 3

Clinically relevant outcomes by treatment assignment

Propofol arm (n=25)Volatile arm (n=25)
Low cardiac output syndrome, n (%)Present4 (16%)4 (16%)
Intra-aortic balloon pump criteria0 (0%)1 (4%)
Vasoactive criteria4 (16%)3 (12%)
Missing data0 (0%)1 (4%)
Atrial fibrillation, n (%)Present2 (8%)5 (20%)
Missing data0 (0%)1 (4%)
Intensive care unit LOSDays median (IQR)2 (2–3)2 (2–4)
Missing data0 (0%)1 (4%)
Hospital LOSDays median (IQR)7 (5–11)10 (7–14)
Missing data0 (0%)1 (4%)
Myocardial injuryTnT (ng/L)
Elevated TnT (>100× 99th URL)4 (16%)4 (16%)
Preoperative TnT median (IQR)19 (11–36)25 (14–41)
Preop missing data2 (8%)1 (4%)
6 hour TnT median (IQR)936 (632–1189)777 (550–1087)
6 hour TnT missing data2 (8%)2 (8%)
Day 1 TnT median (IQR)578 (389–821)504 (304–757)
Day 1 TnT missing data2 (8%)1 (4%)
Day 2 TnT median (IQR)326 (232–453)331 (202–589)
Day 2 TnT missing data3 (12%)2 (8%)
Completed 4 TnT samples18 (78.3%)19 (79.2%)
Major adverse cardiac and cerebrovascular events, n (%)Present7 (28%)4 (16%)
Stroke0 (0%)1 (4%)
Myocardial infarction5 (20%)4 (16%)
Death2 (8%)1 (4%)
Missing data0 (0%)1 (4%)
Cardiac-related mortality at 30 days, n (%)Present1 (4%)1 (4%)
Not recorded0 (0%)1 (4%)
WHO disability assessment scheduleRecorded at 30 days, n (%) (surviving patients, n=22 in each group)19 (76%)20 (80%)
Median (IQR)16 (14–21)20 (15–24)
Change median (IQR)2.0 (−2.0–6.0)2.5 (−1.0–9.0)
Missing data3 (12%)2 (8%)
EQ-5D-5LRecorded at 30 days, n (%) (from surviving patients, n=22 in each group)19 (76%)20 (80%)
Missing data3 (12%)2 (8%)
EQ-5D-5L health statusMedian (IQR)75 (65–85)75 (60–80)
Change in median (IQR)4.0 (−5.0–23.0)−2.5 (−10.0–7.5)
Days alive and at home until 30 days after surgery*Median (IQR)24 (21–30)22.5 (18–30)
Missing data0 (0%)1 (4%)
  • *Of surviving postoperative patients in each group (n=22).

  • EQ-5D−5L, EuroQoL 5-dimension 5-level; LOS, length of stay; TnT, troponin T.