Table 4

Scenario analyses results

ScenarioIncremental costsIncremental QALYsICER
Base case£6410.17£3783
Blanking period implemented£2980.09£3219
Increased relative risk of AF recurrence relative to the number of previous ablations by 10%£3170.18£1722
Increased relative risk of AF resolution relative to the number of previous ablations by 10%£8990.16£5619
Decreased ablation success rate of 30% (proportionally)£5720.18£3252
Decreased incidence of stroke by 30% (proportionally)£6670.17£3977
EQ-5D form was replaced by AF Quality of Life Survey (AFEQT) form with additional utility decrement for higher European Heart Rhythm Association (EHRA) class£6140.08£7759
Changed health state specific stroke relative risk values to values sourced from published literature£3830.23£1690
Increased relative risk of developing heart failure for those in the permanent health state by 10%£6530.17£3830
Average selling price used for all procedure costs£5960.17£3565
2022/2023 cost used for ablation procedure cost£7900.17£4686
  • EQ-5D, EuroQoL 5 Dimensions; ICER, incremental cost-effectiveness ratio; QALY, quality adjusted life-year.