Baseline characteristics in 54 484 patients with out-of-hospital cardiac arrest
Var | Men | Women | P value | SMD |
n | 35 894 | 18 590 | ||
Patient characteristics | ||||
Age—mean (SD) | 67.98 (17.28) | 71.53 (17.73) | <0.001 | 0.202 |
Cause of cardiac arrest (%) | <0.001 | 0.262 | ||
Heart disease | 21 070 (65.8) | 9313 (56.6) | ||
Overdose or intoxication | 968 (3.0) | 419 (2.5) | ||
Trauma or accident | 862 (2.7) | 262 (1.6) | ||
Pulmonary disease | 1377 (4.3) | 1341 (8.2) | ||
Suffocation | 723 (2.3) | 553 (3.4) | ||
Suicide | 760 (2.4) | 343 (2.1) | ||
Drowning | 322 (1.0) | 134 (0.8) | ||
Other | 5929 (18.5) | 4081 (24.8) | ||
Medications prescribed | ||||
Anticoagulant or antiplatelet agent | 13 467 (37.5) | 6303 (33.9) | <0.001 | 0.075 |
Beta-blockers | 11 773 (32.8) | 6513 (35.0) | <0.001 | 0.047 |
ACE inhibitor or ARB | 12 249 (34.1) | 5616 (30.2) | <0.001 | 0.084 |
Diuretics | 9080 (25.3) | 5650 (30.4) | <0.001 | 0.114 |
Lipid lowering drugs | 9266 (25.8) | 3677 (19.8) | <0.001 | 0.144 |
Calcium channel blockers | 5549 (15.5) | 3154 (17.0) | <0.001 | 0.041 |
Antidiabetic drugs | 5618 (15.7) | 2525 (13.6) | <0.001 | 0.059 |
Initial presentation | ||||
Initial rhythm (%) | <0.001 | 0.340 | ||
VF pVT | 8841 (27.8) | 2316 (14.2) | ||
PEA | 5151 (16.2) | 3127 (19.2) | ||
Asystole | 17 772 (56.0) | 10 882 (66.7) | ||
In-hospital interventions | ||||
Coronary angiography performed | 224 (43.8) | 60 (24.6) | <0.001 | 0.412 |
PCI performed | 2597 (34.6) | 628 (18.1) | <0.001 | 0.382 |
CABG performed | 161 (2.2) | 23 (0.7) | <0.001 | 0.127 |
ICD implanted | 973 (13.2) | 216 (6.3) | <0.001 | 0.234 |
ECMO used | 16 (3.1) | 3 (1.3) | 0.214 | 0.127 |
ARB, angiotensin receptor blockers; CABG, coronary artery bypass graft; ECMO, extracorporeal membrane oxygenation; ICD, implantable cardioverter defibrillator; PCI, percutaneous intervention; PEA, pulseless electrical activity; pVT, pulseless ventricular tachycardia; SMD, standardised mean difference; VF, ventricular fibrillation.