Basic hydrodynamics in high-grade aortic regurgitation (AR) with and without prosthesis of the ascending aorta at a heart rate of 70 bpm and stroke volume (SV) of 72 mL
AR+native aorta | AR+Dacron prosthesis | P value | |
Psyst (mm Hg) | 140.5±8.0 | 143.8±8.0 | n.s. |
P diast (mm Hg) | 72.4±9.5 | 66.5±5.9 | n.s. |
PP (mm Hg) | 68±15.4 | 77+7±10.6 | n.s. |
Dp/dt max (mm Hg/s) | 770±156 | 877±207 | n.s. |
EOA (cm2) | 2.3±0.3 | 2.2±0.4 | n.s. |
MPG (mm Hg) | 4.3±1.6 | 4.8±1.6 | n.s. |
MAP (mm Hg) | 95.1±5.6 | 92.3±4.6 | 0.19 |
PPG (mm Hg) | 12.0±2.3 | 13.9±3.8 | n.s. |
SV (mL) | 72±2.8 | 72±2.2 | n.s. |
RF-Vol (mL) | 48.1±9.4 | 47.6±9.5 | n.s. |
RF (%) | 66.5±11.7 | 66.1±12.1 | n.s. |
Aortic CSA-change in systole and diastole (cm2) | 1.5±0.4 | 0.6±0.03 | <0.0001 |
Aortic distensibility (%/mm Hg) | 0.55±0.21 | 0.01±0.007 | <0.001 |
CSA, cross-sectional area; EOA, effective orifice area; MAP, mean arterial pressure; MPG, mean pressure gradient; n.s., not significant; PP, pulse pressure; PPG, pulse pressure gradient; RF, regurgitation fraction.