Multivariable regression models assessing risk factors for tricuspid regurgitation progression in patients with RHD
| Variables | Cox regression model | Fine-Gray model* | ||||
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (years) | 1.708 | 1.343 to 2.172 | <0.001 | 1.417 | 1.108 to 1.813 | 0.006 |
| NYHA functional class III/IV | 2.572 | 1.540 to 4.298 | <0.001 | 1.894 | 1.165 to 3.079 | 0.010 |
| Atrial fibrillation | 1.215 | 0.633 to 2.330 | 0.558 | 1.014 | 0.530 to 1.940 | 0.970 |
| SPAP (mm Hg) | 1.044 | 0.900 to 1.210 | 0.572 | 1.003 | 0.874 to 1.151 | 0.970 |
| PMV | 1.322 | 0.744 to 2.347 | 0.341 | 1.758 | 1.007 to 3.072 | 0.047 |
| RA area (cm2) | 1.521 | 1.101 to 2.102 | 0.011 | 1.662 | 1.290 to 2.141 | <0.001 |
| RV systolic annular velocity (cm/s) | 0.930 | 0.808 to 1.070 | 0.309 | 0.899 | 0.773 to 1.046 | 0.170 |
| RV dysfunction | 2.024 | 1.068 to 3.836 | 0.031 | 1.694 | 0.903 to 3.179 | 0.100 |
*Fine-Gray model dealing with deaths and surgery alternatively as competing risks.
NYHA, New York Heart Association; PMV, percutaneous mitral valvuloplasty; RA, right atrium; RHD, rheumatic heart disease; RV, right ventricular; SPAP, systolic pulmonary artery pressure.