Table 3

Univariable logistic regression analyses in 81 women with Ebstein’s anomaly

MACE (n=8)No MACE (n=73)Univariable logistic regression
OR95% CI
lower limit
95% CI
upper limit
P value
Characteristic
Age, mean (SD), years30.2 (8.4)29.6 (5.9)1.010.881.160.871
BMI, mean (SD)27.0 (6.6)24.1 (3.8)1.090.911.320.346
LMIC3 (37.5)14 (19.2)2.530.5411.860.239
Nulliparity5 (62.5)33 (40.7)2.020.459.090.359
Twin pregnancy*0 (0)2 (2.7)NMNMNMNM
Current smoking*0 (0)1 (1.4)NMNMNMNM
Chronic hypertension1 (12.5)6 (8.2)1.600.1715.220.685
Cardiac medication use before pregnancy2 (25.0)5 (6.8)4.530.7228.550.107
Diabetes mellitus1 (12.5)1 (1.4)8.930.49161.370.138
Atrial fibrillation/flutter1 (12.5)2 (2.7)5.070.4163.210.207
History of heart failure3 (37.5)2 (2.7)21.302.87158.320.003
Cyanosis1 (12.5)3 (4.1)3.330.3136.480.324
NYHA class>I3 (37.5)19 (26.0)1.710.377.830.492
Severe tricuspid valve regurgitation2 (25.0)10 (13.7)2.100.3711.890.402
Tricuspid valve repair*0 (0)7 (9.6)NMNMNMNM
Tricuspid valve replacement1 (12.5)7 (9.6)0.740.086.940.794
  • Data in n (%) unless otherwise specified. Bold script denotes p<0.05. After multiple imputation for age (9.9%), BMI (40.1%), current smoking (22.2%), prior diabetes mellitus (1.2%) and signs of heart failure (1.2%).

  • *OR could not be computed because of complete separation.

  • BMI, body mass index; LMIC, low-income and middle-income country; MACE, major adverse cardiac event; NM, not measurable; NYHA, New York Heart Association .