Table 1

Dosing criteria according to renal guidelines

Dosing criteria for AFEdoxabanApixabanDabigatranRivaroxaban
Normal dosing regime60 mg once per day5 mg two times per day150 mg two times per day20 mg once per day
Reduced dosing regime30 mg once per day2.5 mg two times per day110 mg two times per day15 mg once per day
Renal criteria for dose reductionCrCl 15–50 mL/minCrCl 15–30 mL/min or ≥2 of: Age>80 years, body weight ≤60 kg, creatinine ≥133 umol/LCrCl 30–50 mL/minCrCl 15–50 mL/min
Contraindication (renal)CrCl ≤15 mL/minCrCl ≤15 mL/minCrCl ≤30 mL/minCrCl ≤15 mL/min
  • CrCI, creatinine clearance.