Echocardiography parameters at 30 days for patients with moderately-severe AS and severe AS
| Moderately-severe AS (n=113) | Severe AS (n=1300) | |||||
| TAVR (n=66) | SAVR (n=47) | P value | TAVR (n=661) | SAVR (n=639) | P value | |
| Aortic valve area, cm2 | 2.5±0.7 (56) | 2.0±0.6 (41) | <0.001 | 2.2±0.6 (558) | 2.0±0.6 (509) | <0.001 |
| Aortic Valve Area Index, cm2/m2 | 1.23±0.39 (56) | 0.98±0.27 (41) | <0.001 | 1.10±0.28 (557) | 1.04±0.29 (509) | <0.001 |
| Peak velocity, m/s | 1.9±0.5 (65) | 2.1±0.4 (44) | 0.03 | 2.0±0.4 (641) | 2.2±0.4 (600) | <0.001 |
| Mean pressure gradient, mm Hg | 8.4±4.8 (65) | 10.0±3.4 (44) | 0.04 | 8.4±3.3 (641) | 10.6±4.1 (600) | <0.001 |
| Dimensionless Velocity Index | 0.61±0.14 (61) | 0.51±0.08 (43) | <0.001 | 0.58±0.13 (612) | 0.51±0.11 (569) | <0.001 |
| Left ventricular ejection fraction, % | 63.1±5.7 (65) | 60.7±11.5 (44) | 0.20 | 64.0±6.9 (656) | 62.6±8.0 (604) | 0.01 |
| Stroke volume, mL | 94.4±21.6 (56) | 80.2±20.8 (41) | 0.002 | 82.5±21.4 (568) | 82.0±23.3 (511) | 0.74 |
| Stroke Volume Index, mL/m2 | 45.6±10.4 (56) | 39.5±10.2 (41) | 0.005 | 41.8±10.2 (567) | 41.8±11.3 (511) | 0.97 |
| Total aortic regurgitation (%) | <0.001 | <0.001 | ||||
| None | 14 (21.5) | 33 (75.0) | 130 (20.0) | 436 (73.6) | ||
| Trace | 28 (43.1) | 8 (18.2) | 261 (40.1) | 124 (20.9) | ||
| Mild/mild to moderate | 22 (33.8) | 3 (6.8) | 235 (36.1) | 29 (4.9) | ||
| Moderate/moderate to severe | 1 (1.5) | 0 (0.0) | 23 (3.5) | 2 (0.3) | ||
| Severe | 0 (0.0) | 0 (0.0) | 2 (0.3) | 1 (0.2) | ||
Data shown as mean±SD, mean±SD (no of patients) or no of patients (%).
AS, aortic stenosis; SAVR, surgical aortic valve replacement; TAVR, transcatheter aortic valve replacement.