Characteristic | General population (n=502 324) | Scoliosis carriers (n=4095) | Padj |
Age at recruitment | 56.50±8.10 | 59.40±7.58 | <0.001 |
White British | 406 131 (81%) | 3344 (82%) | NS |
Sex, female | 261 862 (55%) | 2845 (69%) | <0.001 |
BMI | 27.40±4.80 | 27.00±5.16 | NS |
Auto SBP | 140.00±19.60 | 141.00±20.00 | NS |
Auto DBP | 82.20±10.70 | 81.50±10.80 | NS |
Diabetes | 27 771 (5%) | 212 (5%) | NS |
Hypercholesterolaemia | 92 824 (18%) | 1022 (25%) | <0.001 |
Hypertension | 167 817 (33%) | 1902 (46%) | <0.001 |
Included in UKB CMR cohort | 39 319 (8%) | 224 (5%) | <0.001 |
Heart failure | 10 504 (2%) | 237 (6%) | <0.001 |
Any cardiomyopathy | 3602 (0.7%) | 49 (2%) | NS |
Valve disease | 5145 (1%) | 96 (2%) | <0.001 |
Data are presented as mean±SD or count (%); all variables were adjusted for age and sex to assess significance. White British ancestry was genetically inferred. Padj, p value adjusted for multiple comparisons via Bonferroni correction; significant, Padj <0.05; NS, not significant, Padj >0.05.
BMI, body mass index; CM, cardiomyopathy; CMR, cardiac MRI; DBP, diastolic blood pressure; SBP, systolic blood pressure.