Table 3

Complete case analysis of QoL domains

Domain/analysis	CG95 (2010) vs CMR				SPECT vs CMR
	Estimate	SE	95% CI		Estimate	SE	95% CI
	Estimate	SE	Lower	Upper	Estimate	SE	Lower	Upper
Seattle Angina Questionnaire (UK version) (0=worst, 100=best)
Angina Frequency	−0.023	0.056	−0.133	0.087	0.002	0.044	−0.084	0.088
Angina Stability*	−0.224	0.077	−0.376	−0.073	−0.080	0.064	−0.206	0.046
Physical Limitation	−0.072	0.055	−0.180	0.036	0.035	0.045	−0.054	0.124
Quality of Life	−0.053	0.068	−0.187	0.081	−0.004	0.054	−0.110	0.102
Treatment Satisfaction	0.010	0.060	−0.108	0.128	0.106	0.048	0.012	0.200
SF12v2 (0=worst, 100=best)
Body Pain*	−0.078	0.070	−0.216	0.060	−0.106	0.059	−0.222	0.011
General Health*	−0.065	0.069	−0.200	0.071	0.005	0.056	−0.104	0.114
Physical Functioning	−0.224	0.083	−0.386	−0.062	−0.036	0.065	−0.164	0.093
Role Performance	−0.100	0.070	−0.238	0.039	0.019	0.059	−0.098	0.136
Physical Component Summary	−0.052	0.025	−0.101	−0.003	−0.016	0.021	−0.057	0.024
Mental Health	−0.043	0.063	−0.167	0.081	0.044	0.052	−0.058	0.146
Role Emotional	−0.061	0.071	−0.201	0.079	0.002	0.060	−0.116	0.121
Social Functioning*	−0.083	0.076	−0.232	0.067	−0.030	0.064	−0.156	0.097
Vitality*	−0.026	0.074	−0.171	0.120	0.074	0.060	−0.045	0.192
Mental Component Summary	−0.006	0.028	−0.061	0.050	0.020	0.023	−0.026	0.065
EQ-5D-3L (−0.594=worst, 1=perfect health)
Utility26	−0.0009	0.0007	−0.0022	0.0004	−0.0007	0.0006	−0.0018	0.0004
EQ-5D-5L (−0.281=worst, 1=perfect health)
Utility27	−0.0009	0.0005	−0.0019	0.0001	−0.0006	0.0004	−0.0014	0.0001

Estimates given are the arm–time interaction effects, estimating by how much the NICE CG95 and SPECT arm scores change per month, relative to those in the CMR arm. Negative values represent CMR getting better scores (vs comparator) over time, positive values represent CMR patients getting worse scores over time.
*This domain scale derives from a single question comprising five possible responses.
CMR, cardiovascular magnetic resonance; EQ-5D-3L/5L, EuroQol 5-Dimension Questionnaire, 3/5 Levels; NICE, National Institute for Health and Care Excellence; QoL, quality of life; SF12v2, Short Form 12 (V.2) Questionnaire; SPECT, single-photon emission CT.