Risk category | VTE-bleed | AF-bleed | HAS-BLED | ATRIA | ORBIT | ||||||||||
Distribution of points | n/total | IR with 95% CI | Distribution of points | n/total | IR with 95% CI | Distribution of points | n/total | IR with 95% CI | Distribution of points | n/total | IR with 95% CI | Distribution of points | n/total | IR with 95% CI | |
Low | ≤1 points | – | – | ≤2 points | 36/298 | 8.1 (5.7 to 11.2) | 0 points | 10/106 | 7.6 (3.7 to 14.0) | 0–3 points | 81/584 | 8.9 (7.1 to 11.1) | ≤2 points | 130/892 | 9.4 (7.9 to 11.2) |
Medium | N/A | N/A | N/A | N/A | N/A | N/A | 1–2 points | 126/837 | 9.5 (7.9 to 11.3) | 4 points | 26/194 | 8.7 (5.7 to 12.8) | 3 points | 48/243 | 13.6 (10.1 to 18.1) |
High | ≥2 points | 215/1304 | 11.0 (9.6 to 12.5) | ≥3 points | 179/1006 | 11.8 (10.2 to 13.7) | ≥3 points | 79/361 | 15.7 (12.4 to 19.5) | ≥5 points | 108/526 | 14.3 (11.7 to 17.3) | ≥4 points | 37/169 | 16.4 [11.5 to 22.6) |
Total | 215/1304 | 11.0 (9.6 to 12.5) | 215/1304 | 11.0 (9.6 to 12.5) | 215/1304 | 11.0 (9.6 to 12.5) | 215/1304 | 11.0 (9.6 to 12.5) | 215/1304 | 11.0 (9.6 to 12.5) |
AF, atrial fibrillation; IR, incidence rate; N/A, not applicable; n/total, number of bleeding events/ total number of patients in the corresponding risk category; VTE, venous thromboembolism.