Correction (N=45) | PVR (N=16) | P value | |
Age | 4.3 (3.4–6.5) months | 10.4 (7.8–12.7) years | <0.001 |
Male sex | 26 (58%) | 8 (50%) | 0.591 |
BMI (kg/m2) | 15.6±1.5 | 17.3±4.5 | 0.143 |
BSA (m2) | 0.34±0.05 | 1.21±0.39 | <0.001 |
O2 saturation | 92±8 | 99±1 | <0.001 |
Hb | 8.5±1.2 | 8.1±0.64 | 0.092 |
Ht | 0.40±0.06 | 0.39±0.03 | 0.214 |
Prior interventions* | 8 (18%) | 4 (25%) | 0.624 |
mBT | 6 (13%) | 2 (13%) | |
Central AP shunt | 1 (2%) | 1 (6%) | |
RVOT stent | 1 (2%) | – | |
Balloon dilatation | 1 (2%) | – | |
Stent LPA | – | 1 (6%) | |
Prostin | 3 (7%) | 2 (13%) | 0.465 |
Extracardiac defects | 1 (2%) | 2 (13%) | 0.102 |
Bilateral clubfoot | Familial hypercholesterolaemia | ||
Prematurity (29+1) | |||
CMR parameters | |||
LV EDVi (mL/m2) | 76 (66–81) | ||
LV ESVi (mL/m2) | 30 (28–40) | ||
LV SVi (mL/m2) | 40 (36–45) | ||
LV EF (%) | 56 (50–61) | ||
RV EDVi (mL/m2) | 153 (113–164) | ||
RV ESVi (mL/m2) | 74 (70–93) | ||
RV SVi (mL/m2) | 69 (54–79) | ||
RV EF (%) | 42 (40–53) | ||
PR fraction (%) | 43 (35–52) | ||
Intervention | |||
TAP | 33 (73%) | – | – |
Total surgical duration | 310 (276–354) | 261 (239–336) | 0.030 |
Perfusion duration | 128 (111–148) | 83 (61–101) | <0.001 |
Cross-clamp duration | 93 (74–106) | 0 (0–26) | <0.001 |
Bold denotes a statistically significant p value.
*All patients with PVR underwent prior ToF repair, and these procedures were not considered a prior intervention for comparisons with the group undergoing ToF repair. One patient with ToF repair previously underwent both (unsuccessful) mBT and central AP shunt.
AP, aortopulmonary; BMI, body mass index; BSA, body surface area; CMR, cardiac magnetic resonance; EDVi, end-diastolic volume index; EF, ejection fraction; ESVi, end-systolic volume index; Hb, haematocrit; Hb, haemoglobin; LPA, left pulmonary artery; LV, left ventricular; mBT, modified Blalock-(Thomas-)Taussig shunt; PR, pulmonary regurgitation; PVR, pulmonary valve replacement; RV, right ventricular; RVOT, right ventricular outflow tract; SVi, stroke volume index; TAP, transannular patch; ToF, tetralogy of Fallot .