Restenosis following PCI by aspects of pregnancy history in per segment analyses
| Model I | Model II | Model III | ||||
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
| Preterm delivery (PTD) (events/segment years) | ||||||
| No PTD (278/13 204) | 1 (reference) | 1 (reference) | 1 (reference) | |||
| Ever PTD (65/2.776) | 1.08 (0.77 to 1.53) | 0.65 | 1.17 (0.83 to 1.65) | 0.37 | 1.09 (0.77 to 1.55) | 0.62 |
| Late PTD (50/1933) | 1.21 (0.82 to 1.78) | 0.35 | 1.28 (0.87 to 1.88) | 0.21 | 1.19 (0.81 to 1.76) | 0.37 |
| Very PTD (15/843) | 0.81 (0.44 to 1.50) | 0.50 | 0.91 (0.48 to 1.70) | 0.76 | 0.85 (0.45 to 1.59) | 0.60 |
| Small for gestational age (SGA) (events / segment years) | ||||||
| No SGA (299/14 073) | 1 (reference) | 1 (reference) | 1 (reference) | |||
| Ever SGA (44/1907) | 1.09 (0.72 to 1.65) | 0.69 | 1.10 (0.72 to 1.66) | 0.69 | 1.13 (0.75 to 1.72) | 0.56 |
| Parity at time of PCI (events / segment years) | ||||||
| Parity 1 (70/3332) | 1 (reference) | 1 (reference) | 1 (reference) | |||
| Parity 2–3 (235/11 029) | 1.00 (0.71 to 1.42) | 0.99 | 1.08 (0.76 to 1.53) | 0.69 | 1.13 (0.79 to 1.61) | 0.51 |
| Parity >4 (38/1618) | 1.09 (0.66 to 1.80) | 0.73 | 1.22 (0.73 to 2.02) | 0.45 | 1.27 (0.77 to 2.11) | 0.35 |
| Age at first delivery (years) (events/segment years) | ||||||
| Age <20 (46/2041) | 1 (reference) | 1 (reference) | 1 (reference) | |||
| Age 20–34 (283/13 187) | 1.00 (0.67 to 1.49) | 0.99 | 0.90 (0.60 to 1.35) | 0.63 | 0.90 (0.60 to 1.37) | 0.63 |
| Age >35 (14/751) | 0.87 (0.43 to 1.75) | 0.69 | 0.74 (0.36 to 1.53) | 0.42 | 0.73 (0.35 to 1.52) | 0.40 |
Model I: age at index PCI.
Model II: additionally accounted for indication of PCI (STEMI, NSTEMI, unstable CAD, stable CAD, other); year of procedure (2006–2009, 2010–2013, 2014–2017); treated vessel (RCA, left main, LAD, LCX, other); class of stenosis (A, B1, B2 or C); type of device(s) (BMS only, (BMS, predilation with balloon), DES only (DES, predilation with balloon),(Balloon only, drug coated) or (Balloon only, not drug coated)); length of stent; stent diameter >3 mm.
Model III: additionally accounted for diabetes; hypertension; dyslipidaemia; smoking; previous MI.
Results from multiple imputation analysis.
BMS, bare metal stent; CAD, coronary artery disease; DES, drug-eluting stent; LAD, left anterior descending coronary artery; LCX, left circumflex coronary artery; LMS, left main stem; MI, myocardial infarction; PCI, percutaneous coronary intervention; PTD, preterm delivery; RCA, right coronary artery; SGA, small for gestational age.