CMR abnormalities in long Covid at 6 and 12 months postinfection
6 months | 12 months | ||||||||
CMR abnormalities n=102 | No CMR abnormalities n=424 | P value | CMR abnormalities and hospitalised, n=19 | CMR abnormalities not hospitalised, n=83 | P value | Ongoing CMR abnormalities n=41 | Resolved CMR abnormalities n=30 | P value | |
Elevated T1 | 46 (45%) | 0 (0%) | <0.001 | 13 (68%) | 33 (40%) | 0.02 | 13 (32%) | 0 (0%) | <0.001 |
Left ventricle | |||||||||
High end diastolic volume | 4 (3.9%) | 0 (0%) | 0.001 | 1 (5.3%) | 3 (3.6%) | 0.6 | 2 (4.9%) | 0 (0%) | 0.32 |
High end systolic volume | 6 (5.9%) | 4 (0.9%) | 0.005 | 1 (5.3%) | 5 (6.0%) | 1 | 3 (7.3%) | 0 (0%) | 0.15 |
Low ejection fraction | 21 (21%) | 0 (0%) | <0.001 | 5 (26%) | 16 (19%) | 0.5 | 9 (22%) | 0 (0%) | 0.008 |
High stroke volume | 1 (1.0%) | 3 (0.7%) | 0.58 | 0 (0%) | 1 (1.2%) | 1 | 0 (0%) | 0 (0%) | 1 |
High ventricular muscle mass | 6 (5.9%) | 18 (4.2%) | 0.44 | 2 (11%) | 4 (4.8%) | 0.3 | 2 (4.9%) | 2 (6.7%) | 0.60 |
High ventricular maximum wall thickness | 11 (11%) | 26 (6.1%) | 0.09 | 3 (17%) | 8 (9.6%) | 0.4 | 4 (9.8%) | 4 (13%) | 0.23 |
Low global circumferential strain | 11 (11%) | 13 (3.1%) | 0.002 | 2 (11%) | 9 (11%) | 1 | 6 (15%) | 1 (3.3%) | 0.17 |
Low global longitudinal strain | 21 (21%) | 0 (0%) | <0.001 | 1 (5.6%) | 20 (25%) | 0.1 | 7 (17%) | 0 (0%) | 0.02 |
Right ventricle | |||||||||
High end diastolic volume | 6 (5.9%) | 0 (0%) | <0.001 | 2 (11%) | 4 (4.8%) | 0.3 | 3 (7.3%) | 0 (0%) | 0.15 |
High end systolic volume | 7 (6.9%) | 2 (0.5%) | <0.001 | 3 (16%) | 4 (4.8%) | 0.1 | 3 (7.3%) | 2 (6.7%) | 0.79 |
Low ejection fraction | 21 (21%) | 0 (0%) | <0.001 | 4 (21%) | 17 (20%) | 1 | 12 (29%) | 0 (0%) | <0.001 |
High stroke volume | 4 (3.9%) | 0 (0%) | 0.001 | 1 (5.3%) | 3 (3.6%) | 0.6 | 2 (4.9%) | 0 (0%) | 0.32 |
Prevalence of abnormal CMR findings at 6 and 12 months in individuals with Long Covid.
p ≤0.05 are in bold.
CMR, cardiac MR.