CMR metrics in those with between ongoing and resolved cardiac abnormalities
| Healthy controls n=92 | 6 months | 12 months | ||||||
| CMR abnormalities ongoing at 12 months, n=41 | CMR abnormalities resolving at 12 months, n=41 | P value | CMR abnormalities ongoing at 12 months, N=41 | CMR abnormalities resolving at 12 months, N=30 | P value | |||
| Global T1 (ms) | 1.5T | 968 (962, 988) | 974 (35) | 987 (31) | 0.2 | 982 (26) | 970 (36) | 0.2 |
| 3T | 1172 (1150, 1192) | 1196 (37) | 1200 (27) | 0.8 | 1200 (1172,1209) | 1194 (1188, 1204) | 0.9 | |
| Left ventricle | ||||||||
| End diastolic volume (mL) | 86 (79, 97) | 88 (73, 97) | 80 (70, 88) | 0.18 | 86 (16) | 82 (17) | 0.30 | |
| End systolic volume (mL) | 35 (31, 41) | 39 (30, 46) | 34 (28, 41) | 0.07 | 37 (10) | 33 (8) | 0.07 | |
| Ejection fraction (%) | 59.5 (56.6, 62.7) | 55.0 (5.8) | 58.1 (6.0) | 0.04 | 57.7 (6.0) | 60.0 (3.9) | 0.05 | |
| Stroke volume (mL) | 52 (46, 58) | 45 (40, 53) | 46 (43, 50) | 0.99 | 48 (43, 54) | 48 (42, 53) | 0.96 | |
| Ventricular muscle mass (g) | 78 (64, 96) | 87 (19) | 85 (24) | 0.72 | 86 (76, 100) | 84 (68, 108) | 0.79 | |
| Ventricular max wall thickness (mm) | 8.91 (8.16, 10.20) | 9.45 (8.46, 10.50) | 9.24 (8.30, 10.33) | 0.50 | 9.75 (8.77, 10.74) | 9.61 (8.64, 10.58) | 0.56 | |
| Global circumferential strain (%) | −21.28 (2.31) | −19.64 (2.67) | −21.16 (2.44) | 0.02 | −20.43 (2.68) | −21.34 (2.16) | 0.13 | |
| Global longitudinal strain (%) | −14.68 (−15.95, –13.69) | −12.85 (−14.56, –11.49) | −13.93 (−15.03, –11.89) | 0.28 | −13.29 (2.59) | −14.49 (2.13) | 0.04 | |
| Right ventricle | ||||||||
| End diastolic volume (mL) | 87 (78, 101) | 83 (69, 95) | 80 (67, 88) | 0.52 | 81 (72, 98) | 82 (68, 91) | 0.43 | |
| End systolic volume (mL) | 38 (31, 45) | 37 (30, 46) | 34 (27, 39) | 0.16 | 36 (29, 43) | 34 (24, 40) | 0.18 | |
| Ejection fraction (%) | 57.6 (4.5) | 54.9 (5.7) | 57.3 (5.5) | 0.09 | 56.1 (6.1) | 58.9 (5.1) | 0.04 | |
| High stroke volume (mL) | 50 (45, 58) | 44 (39, 52) | 46 (39, 49) | 0.66 | 46 (40, 53) | 46 (41, 50) | 0.96 | |
Detailed findings of CMR at 6 and 12 months in individuals with ongoing and resolved cardiac abnormalities. Values are presented as mean (SD) and p values calculated with t-test when the data were normally distributed. For variables where data were not normally distributed data is presented with median (IQR) and p values are calculated with Wilcoxon rank sum test.
p ≤0.05 are in bold.
CMR, cardiac MR.