Multiorgan impairment (non-cardiac) in individuals at baseline and follow-up
| 6 months | 12 months | |||||||||
| Overall cohort n=534 | CMR abnormalities n=102 | No CMR abnormalities n=424 | P value | CMR abnormalities and hospitalised, n=19 | CMR abnormalities not hospitalised, n=83 | P value | Ongoing CMR abnormalities n=41 | Resolved CMR abnormalities n=30 | P value | |
| Liver | ||||||||||
| cT1 (high) | 58 (11%) | 13 (13%) | 43 (10%) | 0.48 | 3 (16%) | 10 (12%) | 0.71 | 6 (15%) | 1 (3.4%) | 0.23 |
| PDFF (high) | 119 (24%) | 25 (26%) | 92 (24%) | 0.62 | 6 (33%) | 19 (25%) | 0.55 | 9 (23%) | 5 (17%) | 0.56 |
| Volume (high) | 35 (6.6%) | 6 (5.9%) | 29 (6.9%) | 0.72 | 2 (11%) | 4 (4.8%) | 0.31 | 3 (7.3%) | 3 (10%) | 0.69 |
| Kidneys | ||||||||||
| Cortex T1 both kidneys (high) | 28 (5.3%) | 8 (7.8%) | 20 (4.8%) | 0.21 | 3 (16%) | 5 (6.0%) | 0.17 | 2 (4.9%) | 0 (0%) | 0.51 |
| Volume, both kidneys (high) | 18 (3.4%) | 6 (5.9%) | 12 (2.9%) | 0.14 | 3 (16%) | 3 (3.6%) | 0.08 | 2 (4.9%) | 2 (6.9%) | 1 |
| Left cortex T1 (high) | 61 (12%) | 12 (12%) | 48 (11%) | 0.92 | 5 (26%) | 7 (8.4%) | 0.04 | 4 (9.8%) | 3 (10%) | 1 |
| Right cortex T1 (high) | 46 (8.7%) | 8 (7.8%) | 38 (9.1%) | 0.70 | 3 (16%) | 5 (6.0%) | 0.17 | 5 (12%) | 1 (3.4%) | 0.40 |
| Left volume (high) | 28 (5.3%) | 7 (6.9%) | 21 (5.0%) | 0.45 | 3 (16%) | 4 (4.8%) | 0.12 | 2 (4.9%) | 2 (6.9%) | 1 |
| Right volume (high) | 38 (7.2%) | 8 (7.8%) | 30 (7.1%) | 0.81 | 4 (21%) | 4 (4.8%) | 0.04 | 4 (9.8%) | 2 (6.9%) | 1 |
| Pancreas | ||||||||||
| T1 (high) | 46 (9.1%) | 8 (8.4%) | 37 (9.2%) | 0.81 | 2 (11%) | 6 (7.8%) | 0.64 | 2 (5.9%) | 4 (17%) | 0.22 |
| PDFF (high) | 77 (15%) | 14 (14%) | 62 (15%) | 0.86 | 4 (22%) | 10 (12%) | 0.28 | 4 (11%) | 6 (23%) | 0.30 |
| Spleen | ||||||||||
| Volume (high) | 42 (7.9%) | 6 (5.9%) | 36 (8.6%) | 0.37 | 1 (5.3%) | 5 (6.0%) | 1 | 4 (9.8%) | 1 (3.4%) | 0.39 |
| Length (high) | 43 (8.1%) | 8 (7.8%) | 35 (8.3%) | 0.88 | 1 (5.3%) | 7 (8.4%) | 1 | 3 (7.3%) | 0 (0%) | 0.26 |
| Lungs | ||||||||||
| Total deep fractional area change (low) | 12 (2.4%) | 10 (2.5%) | 2 (2.2%) | 1 | 0 (0%) | 2 (2.7%) | 1 | 0 (0%) | 0 (0%) | 1 |
Prevalence of abnormal CMR findings for multiorgan scans at 6 and 12 months in individuals with Long Covid.
p ≤0.05 are in bold.
CMR, cardiac MR; PDFF, proton-density fat fraction; PDFF, proton-density fat fraction.