Table 3

Bivariate Cox regression analysis—all-cause and cardiovascular mortality

All-cause mortalityCardiovascular mortality
HR95% CIP valueHR95% CIP value
Age (vs <65 years)
 65–75 years1.781.32 to 2.391.510.93 to 1.42NS
 75–85 years2.521.93 to 3.30<0.0012.111.43 to 3.12<0.001
 >85 years4.123.13 to 5.423.782.55 to 5.61<0.001
Male (vs female)1.251.09 to 1.450.0021.161.08 to 1.25<0.001
AF (vs no AF)1.111.04 to 1.190.0031.261.04 to 1.540.02
eRVSP ≥45 mm Hg (vs <45 mm Hg)2.341.87 to 2.93<0.0011.911.51 to 2.41<0.001
≥Moderate TR1.250.99 to 1.57NS1.371.12 to 1.680.002
≥Moderate RV dysfunction1.461.18 to 1.8NS1.050.74-1.50NS
LV EF (vs EF >60%)
 50%–60%1.010.91 to 1.17NS1.020.89 to 1.21NS
 40%–50%1.181.07 to 1.31<0.0011.231.09 to 1.39<0.001
 30%–40%1.651.65 to 1.83<0.0011.561.39 to 1.80<0.001
 <30%2.232.02 to 2.46<0.0012.742.46 to 3.05<0.001
VFMR (vs AFMR)1.571.47 to 1.68<0.0011.731.60 to 1.88<0.001
  • AFMR, atrial functional mitral regurgitation; EF, ejection fraction; eRVSP, estimated right ventricular systolic pressure; LV, left ventricular; NS, not significant; RV, right ventricular; TR, tricuspid regurgitation; VFMR, ventricular FMR.