Table 2

Independent predictors of ischaemic and bleeding events based on the recalibrated model

	Composite of ischaemic events			Bleeding events
	Adjusted HR (95% CI)	t statistic	P value	Adjusted HR (95% CI)	t statistic	P value
Age (≥75)	0.98 (0.58 to 1.65)	0.004	0.95
Anaemia	0.98 (0.80 to 1.19)	0.06	0.81
Previous PCI	1.10 (0.89 to 1.37)	0.77	0.38
Previous CABG	0.83 (0.53 to 1.31)	0.63	0.43
CKD	1.56 (1.07 to 2.27)	5.37	0.02
Non-insulin DM	1.10 (0.88 to 1.36)	0.68	0.41
Insulin DM	1.31 (0.85 to 2.02)	1.53	0.22
Severe CKD	1.29 (1.05 to 1.58)	6.01	0.01	1.19 (0.99 to 1.44)	3.35	0.07
PVD	2.18 (1.73 to 2.73)	45.0	<0.001	1.42 (1.13 to 1.79)	8.74	0.003
CHF	1.15 (0.94 to 1.41)	1.79	0.18	1.06 (0.89 to 1.27)	0.43	0.51
Atrial fibrillation	1.12 (0.80 to 1.19)	0.89	0.34	1.11 (0.90 to 1.38)	0.90	0.34
Age (<80)				0.97 (0.74 to 1.27)	0.05	0.82
BMI				1.01 (0.82 to 1.26)	0.01	0.91
Smoking				0.95 (0.75 to 1.20)	0.21	0.65
Malignancy				0.91 (0.68 to 1.23)	0.36	0.55
OMI				0.90 (0.61 to 1.33)	0.29	0.59

BMI, body mass index; CABG, coronary artery bypass grafting; CHF, congestive heart failure; CKD, chronic kidney disease; DM, diabetes; OMI, old myocardial infarction; PCI, percutaneous coronary intervention; PVD, peripheral vessel disease.