Table 3

Top 10 national priorities for research in child/antenatal congenital heart disease (CHD)

RankPriority for research
1How can damage to organs (eg, heart, brain, lung, kidney, bowel) during heart surgery in children with CHD be minimised to reduce complications, especially in those who require multiple operations?
2How can prenatal and postnatal screening strategies (eg, scans, pulse oximetry, novel techniques) be improved to achieve greater accuracy, avoid late diagnosis and reduce complications from CHD?
3What are the effects of CHD, low oxygen saturations and interventions on brain development and behavioural outcomes, and how can these be improved?
4How can the frequency or need for reoperations be reduced for people with CHD (eg, improved valve/conduit longevity or that grow with the patient)?
5How can technology be used to deliver personalised care and improve outcomes in CHD (eg, artificial intelligence, 3D printing, genomics, stem cells, organ regeneration)?
6What is the impact of living with CHD on mental health in children and how can this be improved through access to psychological support and other therapies?
7What is the impact of living with CHD on quality of life in children and how can this be improved?
8How can less invasive interventions be performed for CHD with the same outcomes as open-heart surgery?
9How can the longevity of the Fontan circulation be prolonged and the impact of complications (eg, liver, protein-losing enteropathy, renal, endocrine, fertility) be reduced?
10What are the long-term outcomes and life expectancy of children born with CHD?