Relative changes in echocardiographic and exercise-related variables in patients with or without echocardiographic response, before and 3 months after CRT implantation
| Variable | Non-responder (n=11) | Responder (n=20) | ||
| Baseline | 3 months | Baseline | 3 months | |
| Rest | ||||
| EF (%) | 24.5±8.6 | 24.7±8.0 | 27.7±7.7 | 40.5±8.8* |
| EDV (mL) | 289±105 | 287±101 | 221±72 | 171±52* |
| ESV (mL) | 223±102 | 218±92 | 161±59† | 106±45* |
| Maximal | ||||
| P peak (W) | 97±35 | 102±39 | 107±47 | 118±47* |
| VO2 peak (mL/kg/min) | 14.8±3.9 | 16.0±3.2 | 17.3±6.1 | 19.7±6.6* |
| OUES | 1445±479 | 1610±520 | 1610±521 | 1943±586* |
| VE/VCO2 slope | 38.9±9.9 | 37±6.1 | 34.9±8.4 | 31.7±7.0* |
| Submaximal | ||||
| τVO2 on (s) | 87.2±39.1 | 90.1±48.8 | 58.6±34.2 | 55.4±32.2 |
| τVO2 rec (s) | 79.5±21.4 | 67.0±19.4 | 75.0±47.3 | 57.6±17.3 |
Values presented as mean±SD.
*p<0.05 for within-group difference.
†p<0.05 for between group difference at baseline.
CRT, cardiac resynchronisation therapy; EDV, end-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; OUES, oxygen uptake efficiency slope; P, performance; VE/VCO2 slope, minute ventilation for CO2 elimination; τVO2, time constant of oxygen uptake.