Baseline clinical characteristics
| No NRI N=35 611 | NRI N=1134 | NDR N=225 | P value | |
| Age (years) | 65.3±12.1 | 71.2±12.8 | 65.0±13.3 | <0.001 |
| Female sex | 8381 (23.5) | 345 (30.4) | 49 (21.8) | <0.001 |
| Length of stay (days) | 3 (1–4) | 6 (4–11) | 10 (4–19) | <0.001 |
| BMI (kg/m2) | 28.8±5.5 | 28.2±5.6 | 28.9±6.0 | <0.001 |
| Previous PCI | 10 447 (29.3) | 270 (23.8) | 44 (19.7) | <0.001 |
| Previous CABG | 2406 (6.8) | 105 (9.3) | 15 (6.7) | 0.004 |
| Diabetes mellitus | 7857 (22.1) | 431 (38.0) | 85 (38.1) | <0.001 |
| Peripheral vascular disease | 1222 (3.4) | 93 (8.2) | 24 (10.8) | <0.001 |
| Cerebrovascular disease | 1331 (3.7) | 87 (7.7) | 18 (8.1) | <0.001 |
| Renal function (eGFR; mL/min/1.73 m2) | ||||
| Stages I–II (>60) | 25 944 (72.8) | 488 (43.0) | 89 (39.6) | <0.001 |
| Stage IIIa (45–59) | 3761 (10.6) | 214 (18.9) | 40 (17.8) | <0.001 |
| Stage IIIb (30–44) | 2144 (6.0) | 193 (17.0) | 32 (14.2) | <0.001 |
| Stages IV–V (<30) | 882 (2.4) | 157 (13.8) | 50 (22.2) | <0.001 |
| Chronic dialysis | 437 (1.2) | 59 (5.21) | NA | <0.001 |
| LVEF | ||||
| Normal (≥50%) | 19 821 (63.1) | 358 (34.7) | 41 (19.9) | <0.001 |
| Mild (45–49%) | 6399 (20.4) | 209 (20.3) | 34 16.5) | |
| Moderate (35–44%) | 3604 (11.5) | 235 (22.8) | 49 23.8) | |
| Severe (<35%) | 1569 (5.0) | 229 (22.2) | 82 (39.8) | |
| Clinical presentation | ||||
| STEMI | 9678 (27.2) | 595 (52.5) | 134 (59.6) | <0.001 |
| NSTEMI | 9650 (27.1) | 283 (25.0) | 50 22.7) | |
| UAP | 2430 (6.8) | 43 (3.8) | 3 (1.3) | |
| Non-ACS | 13 853 (38.9) | 213 (18.8) | 37 (16.4) | |
| Cardiogenic shock | 781 (2.2) | 204 (18.0) | 100 (44.4) | <0.001 |
| OHCA | 922 (2.6) | 101 (8.9) | 56 (24.9) | <0.001 |
| IHCA | 560 (1.6) | 80 (7.1) | 46 (20.5) | <0.001 |
| Urgent PCI | 21 749 (61.1) | 944 (83.3) | 200 (88.9) | <0.001 |
Values are expressed as mean±SD or n (%). Length of stay expressed as median days (IQR).
ACS, acute coronary syndrome; BMI, body mass index; CABG, coronary artery bypass graft; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; IHCA, In hospital cardiac arrest; LVEF, left ventricular ejection fraction; NDR, new dialysis requirement; NRI, new renal impairment; NSTEMI, non-ST elevation myocardial infarction; OHCA, out-of-hospital cardiac arrest; PCI, percutaneous coronary intervention; STEMI, ST elevation myocardial infarction; UAP, unstable angina pectoris.