Baseline and procedural characteristics according to annual operator PPCI volume
| Clinical characteristics | Operator volume | |||
| Low (n=1122) | Intermediate (n=1284) | High (n=1297) | P value | |
| No of PPCI per year, median (IQR)† | 27 (9) | 100 (24) | 113 (9) | <0.01* |
| Out-of-hours PPCI n (%)† | 767 (68.4) | 733 (57.1) | 657 (50.7) | <0.01* |
| Age in years, median (IQR) | 63(19) | 63(20) | 63(20) | 0.88 |
| Male n (%) | 828 (73.8) | 950 (74.0) | 928 (71.5) | 0.31 |
| Diabetes mellitus n (%) | 165 (14.7) | 160 (12.5) | 195 (15.0) | 0.38 |
| Current/ex-smoker n (%) | 744 (66.3) | 857 (66.7) | 864 (66.6) | 0.99 |
| Hypertension n (%) | 451 (40.2) | 488 (38.0) | 490 (37.8) | 0.44 |
| Hypercholesterolaemia n (%) | 351 (31.3) | 398 (31.0) | 409 (31.5) | 0.90 |
| Renal insufficiency n (%) | 26 (2.3) | 33 (2.6) | 38 (2.9) | 0.76 |
| Previous MI n (%)* | 137 (12.2) | 162 (12.6) | 161 (12.4) | 0.78 |
| Peripheral/Cerebrovascular disease n (%) | 82 (7.3) | 95 (7.4) | 110 (8.5) | 0.62 |
| Cardiac arrest n (%) | 92 (8.2) | 134 (10.4) | 128 (9.9) | 0.16 |
| Door-to-balloon time in minutes median (IQR) | 51(29) | 47(30) | 53(31) | <0.01* |
| Radial access n (%) | 694 (61.9) | 822 (64.0) | 866 (66.8) | 0.04* |
| Multivessel PCI n (%)† | 110 (9.8) | 104 (8.1) | 109 (8.4) | 0.30 |
| Stent implantation n (%) | 1029 (91.7) | 1206 (93.9) | 1232 (95.0) | <0.01* |
| Third generation P2Y12-receptor inhibitor n (%) | 628 (56.0) | 747 (58.2) | 680 (52.4) | 0.01* |
| Glycoprotein IIb/IIIa antagonist n (%) | 215 (19.2) | 156 (12.1) | 216 (16.7) | <0.01* |
| Bivalirudin n (%) | 1065 (94.9) | 1221 (95.1) | 1219 (94.0) | 0.41 |
| Aspiration thrombectomy n (%) | 759 (67.7) | 982 (76.5) | 850 (65.6) | <0.01* |
| Post-procedural TIMI three flow in IRA n (%)§ | 956 (88.3) | 1155 (92.7) | 1157 (92.0) | <0.01* |
*p≤0.05. Data are expressed in median (IQR), or number (%) as described.
Percentages are reported to the nearest tenth of a percent; p values are quoted to two decimal places and all other values are rounded to the nearest integer.20
IRA, infarct-related artery; MI, myocardial infarction; PPCI, primary percutaneous coronary intervention; TIMI, thrombolysis in myocardial infarction.