Demographics and comorbidities of incident valve disease
| No valve disease (N=472 328) | Any valve disease (N=13 615) | Mitral valve prolapse (N=1119) | Mitral regurgitation (N=6900) | Mitral stenosis (N=2095) | Aortic regurgitation (N=4238) | Aortic stenosis (N=6020) | Tricuspid regurgitation (N=1664) | |
| Female, n (%) | 259 071 (55) | 5980 (44) | 497 (44) | 3242 (47) | 1107 (3) | 1829 (43) | 2443 (41) | 822 (49) |
| BMI >30 kg/m2, n (%) | 114 072 (24) | 4418 (33) | 144 (13) | 1969 (27) | 557 (27) | 1320 (31) | 2228 (37) | 561 (34) |
| SBP (mmHg) | 140±20 | 145±21 | 141±20 | 144±21 | 143±21 | 145±21 | 147±21 | 144±21 |
| Smoking (%) | 6722 (1) | 513 (4) | 26 (2) | 207 (3) | 15 (1) | 94 (2) | 205 (3) | 86 (5) |
| Dyslipidaemia, n(%) | 9958 (2) | 1855 (14) | 105 (9) | 794 (11.5) | 47 (2.2) | 360 (8.5) | 776 (12.9) | 222 (13.3) |
| Diabetes, n (%) | 9564 (2.0) | 1527 (11.2) | 37 (3.3) | 590 (8.6) | 40 (1.9) | 225 (5.3) | 735 (12.2) | 229 (13.8) |
| CAD, n (%) | 4491 (1.0) | 2069 (15.2) | 119 (10.6) | 911 (13.2) | 51 (2.4) | 417 (9.8) | 883 (14.7) | 202 (12.1) |
| CHF, n (%) | 1545 (0.3) | 1801 (13.2) | 68 (6.1) | 1098 (15.9) | 99 (4.7) | 254 (6.0) | 430 (7.1) | 395 (23.7) |
| Rheumatic fever, n(%) | 30 (0.0) | 891 (6.5) | 32 (2.9) | 836 (12.1) | 927 (44.3) | 146 (3.5) | 130 (2.2) | 214 (12.9) |
| Infective endocarditis, n (%) | 105 (0.0) | 974 (7.2) | 52 (4.7) | 902 (13.1) | 932 (44.5) | 155 (3.7) | 125 (2.1) | 225 (13.5) |
| Atrial fibrillation and flutter, n (%) | 3965 (0.8) | 3840 (28.2) | 271 (24.2) | 2867 (41.6) | 1022 (48.8) | 1694 (40.0) | 2002 (33.3) | 540 (32.5) |
| Pulmonary hypertension, n(%) | 54 (0.0) | 320 (2.4) | 38 (3.4) | 147 (2.1) | 35 (1.7) | 34 (0.8) | 48 (0.8) | 185 (11.1) |
Values are expressed as mean±SD or n (%).
BMI, body mass index; CAD, coronary artery disease; CHF, congestive heart failure; SBP, systolic blood pressure.