Table 2

Predictors of poor TTR

CharacteristicsCoefficient (95% CI)P value
CKD stages
 eGFR ≥90Reference
 eGFR 60–893.9 (2.2 to 5.6)<0.001
 eGFR 30–593.0 (1.1 to 5.0)0.002
 eGFR 15–29−0.9 (−4.0 to 2.2)0.58
 eGFR <15/dialysis−5.5 (−11.0 to 0.1)0.05
Age (/10 years)0.4 (−0.1 to 1.0)0.12
Sex, female−0.7 (−1.6 to 0.2)0.14
Hypertension0.2 (−0.8 to 1.1)0.70
Diabetes mellitus−2.1 (−3.4 to −0.9)<0.001
Prior stroke/TIA/systemic embolism0.6 (−0.7 to 1.9)0.34
Prior MI0.7 (−1.3 to 2.6)0.50
Prior PCI or CABG0.2 (−1.5 to 1.9)0.82
Heart failure−3.5 (−4.9 to −2.2)<0.001
Peripheral vascular disease−1.8 (−3.9 to 0.3)0.10
COPD−6.3 (−8.2 to −4.5)<0.001
Cancer (within 3 years)−0.2 (−2.1 to 1.8)0.86
Prior major bleeding−1.6 (−3.4 to 0.2)0.08
Acetylsalicylic acid−1.5 (−2.6 to −0.4)0.01
P2Y12 inhibitor0.5 (−2.5 to 3.5)0.74
  • CABG, coronary artery bypass grafting; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; PCI, percutaneous coronary intervention; TIA, transient ischaemic attack; TTR, time in therapeutic range.