Demographic and clinical characteristics of patients undergoing aortic valve replacement
| Variables median (IQR 25–75) n (%) | Total | Biologic prosthesis | Mechanic prosthesis | P value |
| n=80 | n=53 | n=27 | ||
| Age, years | 56.9 (43.4–65.3) | 62.5 (48.9–67.2) | 46.7 (31.8–59.8) | 0.001* |
| Male | 48 (60) | 30 (56.6) | 18 (66.6) | 0.38† |
| BSA (m2) | 1.76±0.17‡ | 1.74±0.16‡ | 1.80±0.18‡ | 0.13§ |
| BMI (kg/m2) | 27.5 (24.4–29.9) | 27.1 (24.2–29.9) | 26.8 (25.3–30.8) | 0.81* |
| NYHA class II | 27 (33.7) | 17 (37) | 10 (32) | 0.65† |
| Smoking | 14 (17.5) | 11 (20.7) | 3 (11.1) | 0.36¶ |
| Obesity | 19 (23.7) | 12 (22.6) | 7 (25.9) | 0.74† |
| Hypertension | 56 (70) | 36 (67.9) | 20 (74) | 0.57 |
| Diabetes | 22 (27.5) | 15 (28.3) | 7 (25.9) | 0.82 |
| Dyslipidaemia | 40 (50) | 24 (45.2) | 16 (59.2) | 0.23 |
| DAVD | 43 (53.7) | 31 (58.4) | 12 (44.4) | 0.23 |
| Statins | 39 (48.7) | 27 (50.9) | 12 (44.4) | 0.58 |
| Haemoglobin (g/L) | 147(131–156) | 145(125–159) | 149(136–157) | 0.50* |
| Serum creatinine (mg/dL) | 0.8 (0.7–1.0) | 0.9 (0.7–1.0) | 0.78 (0.6–0.9) | 0.02* |
| eGFR (mL/min/m2) | 82.9±24‡ | 78.3±24.1‡ | 91.9±21.4‡ | 0.01§ |
| Glucose (mg/dL) | 99 (92.8–112.9) | 100.8 (93.1–113.5) | 96.6 (89.9–108.3) | 0.33* |
| LDL (mg/dL) | 112.8 (88–139.5) | 107.5 (85.2–130.9) | 129 (96.7–155.6) | 0.03 |
| HDL (mg/dL) | 41.2 (36.8–48.5) | 40.8 (36.8–48.5) | 43.6 (36.4–48.6) | 0.71 |
| Triglycerides (mg/dL) | 157 (118.6–197.1) | 147(116-182) | 163.7 (127–263.7) | 0.09 |
| Total cholesterol (mg/dL) | 181 (153–202.5) | 178.5 (147.8–191.8) | 197.2 (162–234.7) | 0.02 |
| Albumin (g/dL) | 4.19 (4.1–4.3) | 4.1 (4–4.3) | 4.3 (4.1–4.5) | 0.03 |
| Uric acid (mg/dL) | 5.82±1.4‡ | 5.8±1.3‡ | 5.8±1.6‡ | 0.85§ |
| ASA | 36(45) | 35(66) | 1 (3.7) | 0.00† |
| OACs | 39 (48.7) | 12 (22.6) | 27(100) | 0.00 |
| Sinus rhythm | 68(85) | 48 (90.5) | 20(74) | 0.55¶ |
*Mann-Whitney U test.
†Pearson’s χ2 test.
‡Mean(±SD).
§Student’s t-test.
¶Fisher’s exact test.
ASA, acetylsalicylic acid; BMI, body mass index; BSA, body surface area; DAVD, degenerative aortic valve disease; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NYHA, New York Heart Association; OACs, oral anticoagulants.