Table 1

Demographic and clinical characteristics of patients undergoing aortic valve replacement

Variables
median (IQR 25–75)
n (%)
TotalBiologic prosthesisMechanic prosthesisP value
n=80n=53n=27
Age, years56.9 (43.4–65.3)62.5 (48.9–67.2)46.7 (31.8–59.8)0.001*
Male48 (60)30 (56.6)18 (66.6)0.38†
BSA (m2)1.76±0.17‡1.74±0.16‡1.80±0.18‡0.13§
BMI (kg/m2)27.5 (24.4–29.9)27.1 (24.2–29.9)26.8 (25.3–30.8)0.81*
NYHA class II27 (33.7)17 (37)10 (32)0.65†
Smoking14 (17.5)11 (20.7)3 (11.1)0.36¶
Obesity19 (23.7)12 (22.6)7 (25.9)0.74†
Hypertension56 (70)36 (67.9)20 (74)0.57
Diabetes22 (27.5)15 (28.3)7 (25.9)0.82
Dyslipidaemia40 (50)24 (45.2)16 (59.2)0.23
DAVD43 (53.7)31 (58.4)12 (44.4)0.23
Statins39 (48.7)27 (50.9)12 (44.4)0.58
Haemoglobin (g/L)147(131–156)145(125–159)149(136–157)0.50*
Serum creatinine (mg/dL)0.8 (0.7–1.0)0.9 (0.7–1.0)0.78 (0.6–0.9)0.02*
eGFR (mL/min/m2)82.9±24‡78.3±24.1‡91.9±21.4‡0.01§
Glucose (mg/dL)99 (92.8–112.9)100.8 (93.1–113.5)96.6 (89.9–108.3)0.33*
LDL (mg/dL)112.8 (88–139.5)107.5 (85.2–130.9)129 (96.7–155.6)0.03
HDL (mg/dL)41.2 (36.8–48.5)40.8 (36.8–48.5)43.6 (36.4–48.6)0.71
Triglycerides (mg/dL)157 (118.6–197.1)147(116-182)163.7 (127–263.7)0.09
Total cholesterol (mg/dL)181 (153–202.5)178.5 (147.8–191.8)197.2 (162–234.7)0.02
Albumin (g/dL)4.19 (4.1–4.3)4.1 (4–4.3)4.3 (4.1–4.5)0.03
Uric acid (mg/dL)5.82±1.4‡5.8±1.3‡5.8±1.6‡0.85§
ASA36(45)35(66)1 (3.7)0.00†
OACs39 (48.7)12 (22.6)27(100)0.00
Sinus rhythm68(85)48 (90.5)20(74)0.55¶
  • *Mann-Whitney U test.

  • †Pearson’s χ2 test.

  • ‡Mean(±SD).

  • §Student’s t-test.

  • ¶Fisher’s exact test.

  • ASA, acetylsalicylic acid; BMI, body mass index; BSA, body surface area; DAVD, degenerative aortic valve disease; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NYHA, New York Heart Association; OACs, oral anticoagulants.