CPET parameters associated with the primary endpoint
| Parameters | Primary EP, n=11 | No primary EP, n=189 | P value | ||
| Mean±SD | 25%–75% | Mean±SD | 25%–75% | ||
| Load duration (s) | 422±112 | 377–612 | 449±121 | 368–625 | >0.05 |
| Max heart rate (beat per min) | 109.2±26.8 | 101–129 | 112±38 | 106–141 | >0.05 |
| Max systolic BP (mm Hg) | 176.5±32.5 | 144–201 | 166±36.6 | 151–188 | >0.05 |
| RER | 0.98±0.08 | 0.88–1.12 | 1.02±0.11 | 0.89–1.15 | >0.05 |
| VE/VCO2 | 27.2±5.9 | 22.8–34.9 | 25.5±6.8 | 19.8–33.8 | >0.05 |
| Maximum load (METS) | 5.6±3.1 | 3.9–8.2 | 6.8±4.3 | 4.4–10.6 | 0.01 |
| Peak O2 consumption (mL/kg/min) | 15.8±5.0 | 12.8–20.1 | 18.5±4.9 | 13.3–22.8 | 0.01 |
| O2 consumption (% of predicted value) | 79.2±11.1 | 59.28–88.1 | 82.4±9.8 | 67.2–91.5 | >0.05 |
| AT (mL/kg/min) | 8.8±3.1 | 7.2–12.8 | 11.5±4.4 | 8.6–14.8 | 0.01 |
| Qualitative data | ||||
| Parameters | Primary EP, n (%) | No EP, n (%) | OR (95% CI) | P value |
| AT<11,0 (mL/kg/min) | 5 | 22 | 6,33 (1.78–22.47) | 0.02 |
| METS<4 | 3 | 13 | 5,11 (1.21–21.58) | 0.015 |
AT, anaerobic threshold; CPET, cardiopulmonary exercise test; EP, end point; METS, metabolic equivalents; RER, respiratory exchange ration; VE/VO2, ventilatory equivalent for carbon dioxide.