Baseline characteristics compared between patients with and without CA
| Variables | No conduction abnormality (n=38) | Conduction abnormality (n=20) | P value |
| Demographics | |||
| Age (years) | 79 (71–85) | 79.5 (68–84) | 0.812 |
| Male gender | 21 (55%) | 12 (60%) | 0.729 |
| Height (cm) | 158 (153–167) | 164 (156–172) | 0.191 |
| Weight (kg) | 71.7±16.1 | 80.6±15.2 | 0.078 |
| Logistic EuroSCORE | 7.5 (5.5–11.9) | 5.5 (2.1–10.7) | 0.197 |
| Comorbidities | |||
| eGFR (mL/min/1.73 m2) | 58.5±17.7 | 60.2±16.5 | 0.724 |
| Diabetes | 8 (21%) | 4 (20%) | 0.925 |
| Hypertension | 23 (60%) | 12 (60%) | 0.969 |
| Pulmonary disease | 11 (29%) | 0 (0%) | 0.008 |
| Previous stroke | 4 (11%) | 2 (10%) | 1 |
| Previous myocardial infarction | 6 (16%) | 1 (5%) | 0.403 |
| Multivessel CAD | 4 (11%) | 2 (10%) | 1 |
| Frailty | 3 (8%) | 2 (10%) | 1 |
| Pre-TAVI echocardiography | |||
| AV maximum velocity (m/s) | 3.4±1.2 | 3.6±1.0 | 0.494 |
| AV peak gradient (mm Hg) | 61.0±30.2 | 60.1±24.3 | 0.927 |
| AV mean gradient (mm Hg) | 34.5±20.8 | 33.3±15.3 | 0.837 |
| LVEF (%) | 53 (38–59) | 55 (39–63) | 0.975 |
| TAPSE (cm) | 2.20±0.62 | 1.93±0.51 | 0.154 |
| Bicuspid valve morphology | |||
| BAV morphology (Sevier’s classification) | Type 0 (AP)=4 (11%) | Type 0 (AP)=6 (30%) | 0.288 |
| Type 0 (lat)=8 (21%) | Type 0 (lat)=1 (5%) | ||
| Type 1 (L-R)=20 (53%) | Type 1 (L-R)=10 (50%) | ||
| Type 1 (R-N)=3 (8%) | Type 1 (R-N)=1 (5%) | ||
| Type 1 (N-L)=2 (5%) | Type 1 (N-L)=2 (10%) | ||
| Type 2 (R-N)=1 (3%) | Type 2 (R-N)=0 (0%) | ||
| Pre-TAVI CT analysis | |||
| Calcium score (adjacent to MS) | 1880 (1073–2605) | 2092 (1232–4075) | 0.421 |
| Calcium volume (adjacent to MS) (mm3) | 1495 (858–2051) | 1658 (961–3223) | 0.401 |
| Calcium score (opposite the MS) | 1056 (591–1560) | 796 (570–1603) | 0.592 |
| Calcium volume (opposite the MS) (mm3) | 837 (472–1242) | 623 (456–1283) | 0.61 |
| Total valve calcium score | 3117 (2042–3971) | 2744 (1920–5956) | 0.924 |
| Total valve calcium volume (mm3) | 2477 (1646–3150) | 2167 (1525–4735) | 0.91 |
| Aortic annulus diameter average (cm) | 2.49±0.31 | 2.56±0.36 | 0.46 |
| Eccentricity Index (cm) | 0.78 (0.73–0.87) | 0.78 (0.75–0.86) | 1 |
| Aortic annulus area (cm2) | 4.87±1.17 | 5.07±1.39 | 0.921 |
| Sinus of valsalva diameter average (cm) | 3.51±0.44 | 3.41±0.59 | 0.581 |
| Sinotubular junction diameter average (cm) | 3.30±0.43 | 3.15±0.63 | 0.534 |
| Ascending aorta diameter average (cm) | 3.77±0.44 | 3.91±0.58 | 0.284 |
| Membranous septum depth (mm) | 6.0 (5.0–8.4) | 5.8 (4.5–7.3) | 0.441 |
| Aortic-annular angulation (degrees) | 160.1±8.4 | 160.0±12.0 | 0.966 |
| Pre-TAVI ECG | |||
| Left axis deviation | 3 (8%) | 1 (5%) | 1.000 |
| First degree heart block | 10 (26%) | 1 (5%) | 0.049 |
| Right bundle branch block | 2 (5%) | 0 (0%) | 0.54 |
Data are presented as mean±SD, median (IQR or number (percentage).
AP, anterior–posterior; AV, aortic valve; BAV, bicuspid aortic valve; CA, conduction abnormalities; CAD, coronary artery disease; eGFR, estimated glomerular filtration rate; L, left; LVEF, left ventricular ejection fraction; MS, membranous septum; N, non-coronary; R, right; TAPSE, tricuspid annular planar systolic excursion.