Univariate and multivariate linear regression analysis of the association between MI and annual progression rate of aortic stenosis
| Parameters | Acute MI Univariate analysis | Acute MI Multivariate analysis* | ||
| MD (95% CI) | P value | MD (95% CI) | P value | |
| AVAi (cm2/m2/year) | −0.013 (−0.021 to −0.005) | 0.001 | −0.013 (−0.023 to −0.003) | 0.0076 |
| AVA (cm2/year) | −0.024 (−0.038 to −0.009) | 0.002 | −0.023 (−0.041 to −0.006) | 0.0086 |
| VTI ratio (/year) | −0.005 (−0.009 to −0.002) | 0.006 | −0.006 (−0.010 to −0.001) | 0.0092 |
| MG (mm Hg/year) | +0.44 (−0.28 to 1.15) | 0.23 | – | – |
| Vpeak (m/s/year) | +0.05 (0.00 to 0.11) | 0.036 | +0.03 (−0.03 to 0.09) | 0.35 |
*Adjusted for age, sex, hypertension, dyslipidaemia, diabetes mellitus, chronic kidney disease, bicuspid aortic valve, smoking history, statin, baseline echocardiographic value of the analysed measurement and annual change in indexed stroke volume.
AVA, aortic valve area; AVAi, indexed aortic valve area; MD, mean difference; MG, mean aortic gradient; MI, myocardial infarction; Vpeak, aortic peak jet velocity; VTI, velocity-time integral.