Table 3

Univariate and multivariate linear regression analysis of the association between MI and annual progression rate of aortic stenosis

ParametersAcute MI
Univariate analysis
Acute MI
Multivariate analysis*
MD (95% CI)P valueMD (95% CI)P value
AVAi (cm2/m2/year)−0.013 (−0.021 to −0.005)0.001−0.013 (−0.023 to −0.003)0.0076
AVA (cm2/year)−0.024 (−0.038 to −0.009)0.002−0.023 (−0.041 to −0.006)0.0086
VTI ratio (/year)−0.005 (−0.009 to −0.002)0.006−0.006 (−0.010 to −0.001)0.0092
MG (mm Hg/year)+0.44 (−0.28 to 1.15)0.23
Vpeak (m/s/year)+0.05 (0.00 to 0.11)0.036+0.03 (−0.03 to 0.09)0.35
  • *Adjusted for age, sex, hypertension, dyslipidaemia, diabetes mellitus, chronic kidney disease, bicuspid aortic valve, smoking history, statin, baseline echocardiographic value of the analysed measurement and annual change in indexed stroke volume.

  • AVA, aortic valve area; AVAi, indexed aortic valve area; MD, mean difference; MG, mean aortic gradient; MI, myocardial infarction; Vpeak, aortic peak jet velocity; VTI, velocity-time integral.