Baseline characteristics among patients with STEMI and association with 1-year mortality (N=568)
Variable | All patients (N=568) | Survivors (n=518) | Non-survivors (n=50) | P Value |
Age, years | 64 [55–72] | 63 [55–71] | 70 [60–79] | <0.001 |
Male | 434 (76.4) | 397 (76.6) | 37 (74.0) | 0.727 |
Ethnicity | ||||
Caucasian | 552 (97.2) | |||
STEMI location — ECG | 0.239 | |||
Anterior | 224 (39.4) | 196 (37.8) | 28 (56.0) | |
Inferior | 281 (49.5) | 262 (50.6) | 19 (38.0) | |
Lateral | 24 (4.2) | 22 (4.2) | 2 (4.0) | |
Posterior | 31 (5.5) | 30 (5.8) | 1 (2.0) | |
LBBB | 6 (1.1) | 6 (1.2) | 0 (0) | |
RBBB | 2 (0.3) | 2 (0.4) | 0 (0) | |
Culprit vessel — coronary angiography | 0.009 | |||
Left anterior descending artery | 220 (38.7) | 201 (38.8) | 19 (38.0) | |
Right coronary artery | 227 (40.0) | 210 (40.5) | 17 (34.0) | |
Left circumflex artery | 95 (16.7) | 89 (17.2) | 6 (12.0) | |
Left main stem | 7 (1.2) | 5 (1.0) | 2 (4.0) | |
Ramus intermedius | 1 (0.2) | 1 (0.2) | 0 (0) | |
Multiple-vessel or Indeterminate | 18 (3.2) | 12 (2.3) | 6 (12.0) | |
Primary intervention | ||||
PPCI | 535 (94.2) | 488 (94.2) | 47 (94.0) | 1.000 |
CABG | 12 (2.1) | 12 (2.1) | 0 (0) | |
Medical management | 21 (3.7) | 18 (3.5) | 3 (6.0) | |
Creatinine, µmol/L | ||||
Median | 76 [69–94] | 76 [69–90] | 135 [93–216] | <0.001 |
Mean | 95.6 (±76.1) | 88.3 (±65.6) | 170.7 (±122.1) | <0.001 |
Peak hs-cTnT, ng/L | ||||
Median | 3110 [1263–6232] | 3002 [1233–5785] | 5966 [1979–13 322] | 0.001 |
Mean | 5124 (±6922) | 4622 (±5814) | 10 319 (±12 823) | 0.003 |
Minimum | 20 | 20 | 24 | |
Maximum | 57 875 | 55 893 | 57 875 | |
Range | 57 855 | 55 873 | 57 851 | |
Time of peak hs-cTnT, days | 1 [0–1] | 1 [0–1] | 1 [0–2] | 0.230 |
LVEF at discharge, %* | 50 [42–52] | 50 [42–52] | 40 [20–47] | <0.001 |
Normal | 273 (48.1) | 265 (51.2) | 8 (16.0) | |
Moderate dysfunction | 199 (35.0) | 187 (36.1) | 12 (24.0) | |
Severe dysfunction | 64 (11.3) | 49 (9.5) | 15 (30.0) |
Data represent the number (percentage) of patients, mean (±SD) or median [IQR]. Mann-Whitney U test was used for comparisons of continuous variables; Fisher’s exact test was used for categorical variables; T-test was used for comparison of means.
*Based on patients with known LVEF at discharge; normal=≥50% / moderate=35%–49% / severe=<35%; n=32 (5.6) for unknown LVEF.
CABG, coronary artery bypass graft; hs-cTnT, high-sensitivity cardiac troponin T; LBBB, left bundle branch block; LVEF, left ventricular ejection fraction; PPCI, primary percutaneous coronary intervention; RBBB, right bundle branch block; STEMI, ST-elevation myocardial infarction.