Baseline demographic and echocardiographic characteristics of the patient population of the two randomised controlled trials
| AVATAR | RECOVERY | |||
| Early surgery | Conservative care | Early surgery | Conservative care | |
| Number of participants | 78 | 79 | 73 | 72 |
| Age (years) | 68 (63–73)* | 69 (64–74.5)* | 65±7.8† | 63.4±10.7† |
| Sex (male, %) | 46 (59) | 44 (55.7) | 37 (51) | 34 (47) |
| Median follow-up (months) | 28 | 35 | 74.4 | 73.2 |
| Demographic parameters | ||||
| BMI (kg/m2) | 27.2 | 27.4 | 24.7 | 24 |
| BSA (m2) | 1.9 (1.8–2.1)* | 1.9 (1.8–2.0)* | 1.69±0.17† | 1.64±0.17† |
| Diabetes mellitus, n (%) | 14 (17.9) | 23 (29.1) | 13 (18) | 7 (10) |
| Hypertension, n (%) | 69 (88.4) | 70 (88.6) | 40 (55) | 39 (54) |
| Smoking, n (%) | 16 (20.5) | 14 (17.7) | 19 (26) | 21 (29) |
| Dyslipidaemia, n (%) | 31 (39.7) | 28 (35.4) | 41 (56) | 42 (58) |
| Echocardiographic parameters | ||||
| AVA, cm2 | 0.73* | 0.74* | 0.63† | 0.64† |
| AVAi, cm2/m2 | 0.37* | 0.37* | 0.38† | 0.39† |
| Vmax, m/s | 4.5* | 4.5* | 5.14† | 5.04† |
| LVEF (%) | 70* | 69* | 64.8† | 64.8† |
| LV mass index, g/m² | 152* | 160* | 135.6† | 133.7† |
Data are presented as available by the relevant published studies.
*Median (IQR).
†Mean±SD.
AVA, aortic valve area; AVAi, indexed aortic valve area; AVATAR, Aortic Valve Replacement versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis; BMI, body mass index; BSA, body surface area; LV, left ventricular; LVEF, left ventricular ejection fraction; RECOVERY, Randomized Comparison of Early Surgery versus Conventional Treatment in Very Severe Aortic Stenosis; Vmax, maximal velocity across the aortic valve.