Modified Duke/ESC 2015 clinical criteria in patients with definite infective endocarditis by pathological criteria and those without histology available
| Clinical criteria | All patients n=80 (%) | Definite by pathological criteria n=45 | No histology available n=35 | |||
| All patients n=45 (%) | Definite IE n=26 (%) | Possible IE n=19 (%) | Definite IE n=28 (%) | Possible IE n=7 (%) | ||
| No of major criteria present | ||||||
| 1 | 38 (47.5) | 25 (55.6) | 6 (23.1) | 19 (100) | 6 (21.4) | 7 (100) |
| 2 | 42 (52.5) | 20 (44.4) | 20 (76.9) | 0 | 22 (78.6) | 0 |
| Category of major criteria present | ||||||
| Imaging major criteria present | 79 (98.8) | 45 (100) | 26 (100) | 19 (100) | 27 (96.4) | 7 (100) |
| Echocardiography | ||||||
| Vegetation | 74 (92.5) | 41 (91) | 26 (100) | 15 (78.9) | 26 (92.9) | 7 (100) |
| Perforation | 32 (40) | 25 (55.6) | 14 (53.8) | 11 (57.9) | 4 (14.3) | 3 (42.9) |
| Abscess | 13 (16.3) | 9 (20) | 4 (15.4) | 5 (26.3) | 3 (10.7) | 1 ((14.3) |
| Dehiscence of a prosthetic valve | 5 (6.3) | 3 (6.7) | 2 (7.7) | 1 (5.3) | 1 (3.6) | 1 (14.3 |
| 18F-FDG PET/CT positive | 4 (5) | 4 (8.9) | 1/1 (3.8) | 3/4 (15.8) | 0/2 | 0/1 |
| Microbiological major criteria present | 42 (52.5) | 20 (44.4) | 20 (76.9) | 0 | 22 (78.6) | 0 |
| No of minor criteria present: | ||||||
| 0 | 6 (7.5) | 5 (11.1) | 1 (3.8)) | 4 (21.1) | 0 | 1 (14.3) |
| 1 | 9 (11.3) | 6 (13.3) | 4 (15.4) | 2 (10.5) | 2 (7.1) | 3 (42.9) |
| 2 | 35 (43.8) | 23 (51.1) | 10 (38.5) | 13 (68.4) | 9 (32.1) | 3 (42.9) |
| 3 | 22 (27.5) | 9 (20) | 9 (34.6) | 0 | 13 (46.4) | 0 |
| 4 | 6 (7.5) | 2 (4.4) | 2 (7.7) | 0 | 4 (14.3) | 0 |
| 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| Category of minor criteria present | ||||||
| Predisposing endocardial abnormality or intravenous drug use | 42 (52.5) | 22 (55) | 16 (64) | 6 (40) | 18 (64.3) | 2 (33.3) |
| Documented fever | 29 (36.3) | 14 (35) | 10 (40) | 4 (26.7) | 14 (50) | 1 (16.7) |
| Vascular phenomena | 35 (43.8) | 14 (35) | 12 (48) | 2 (13.3) | 18 (64.3) | 3 (50) |
| Immunological phenomena | 46 (57.5) | 24 (60) | 17 (68) | 7 (46.7) | 20 (71.4) | 2 (33.3) |
| Microbiological evidence | 19 (23.8) | 13 (32.5) | 4 (16) | 9 (60) | 5 (17.9) | 1 (16.7) |
Echocardiography—Transthoracic echocardiogram and Transoesophageal echocardiogram; 18FDG PET/CT- Cardiac CT with or without18FDG PET/CT.
ESC, European Society of Cardiology; 18FDG PET/CT, 18-fluorodeoxyglucose positron emission tomography; IE, infective endocarditis.