Characteristics of patients with Group I pulmonary hypertension (PH) who were predicted to have Group II PH as based on the OPTICS and H2FPEF scores
| OPTICS score | H2FPEF score | |
| Number | 4 | 10 |
| H2FPEF score | 6.7±1.5 | 7.1±0.9 |
| OPTICS score | 121±14 | 92±27 |
| Diagnosis, n (%) | ||
| IPAH | −4 | −9 |
| PVOD | −1 | |
| Age (years) | 77±9.9 | 74±7.2 |
| Male, n (%) | 2 (50) | 4 (40) |
| BMI (kg/m2) | 30±5.2 | 33±6 |
| Medical history | ||
| Diabetes mellitus, n (%) | 2 (50) | 4 (40) |
| Atrial fibrillation, n (%) | 3 (75) | 9 (90) |
| Systemic hypertension, n (%) | 0 | 3 (30) |
| Dyslipidaemia, n (%) | 4 (100) | 6 (60) |
| Left-heart valvular surgery, n (%) | 2 (50) | 2 (20) |
| ECG index of SV1 +RV6 (mm) | 10±8 | 9.7±4 |
| Transthoracic echocardiogram | ||
| E/e′ ratio | 24±8 | 13.7±5 |
| LA dilation, n (%) | 4 (100) | 8 (80) |
| Right heart catheterisation | ||
| Mean pulmonary artery pressure (mm Hg) | 44±11 | 41.6±7.2 |
| Pulmonary artery wedge pressure (mm Hg) | 11±1.7 | 9.8±3.5 |
| Pulmonary vascular resistance (woods units, WU) | 9.8±0.8 | 8.9±2.3 |
Data are presented as mean±SD or actual number (%) where stated. NS indicates no significant difference between patient groups.
BMI, body mass index; E/e’ ratio, ratio between early mitral inflow velocity and mitral annular early diastolic velocity; HPAH, heritable pulmonary arterial hypertension; IPAH, idiopathic pulmonary arterial hypertension; LA, left atrium; PVOD, pulmonary veno-occlusive disease; SV1+RV6, sum of the s wave in v1 and r wave in v6; T1DM, type 1 diabetes mellitus; T2DM, type 2 diabetes mellitus.