Table 1

Baseline characteristics of statin users and non-users after propensity score matching

Statin users (n=8631)Statin non-users (n=8631)
General characteristics
Age (years)61 (11)61 (13)
Women (n, %)4482 (52)4499 (52)
Ethnicity (n, %)
Native Dutch6753 (78.2)6841 (79.3)
First generation immigrant1297 (15.0)1200 (13.9)
Second generation immigrant581 (6.7)590 (6.8)
Annual personal income (€)€27 860
(€14 647–€48 390)
€28 261
(€14 956–€47 613)
Current smoker (n, %)3543 (41.0)3540 (41.0)
10-year cardiovascular mortality risk (SCORE)
 0%–4%4757 (55.1)4562 (52.9)
 5%–9%2380 (27.6)2175 (25.2)
 ≥10%1493 (17.3)1887 (21.9)
Complaints (n, %)
No of complaints3451 (40.0)3389 (39.3)
04925 (57.1)5014 (58.1)
1235 (2.7)216 (2.5)
220 (0.2)12 (0.1)
≥3
Chest pain3176 (36.8)3158 (36.6)
Dyspnoea778 (9.0)759 (8.8)
Fatigue277 (3.2)273 (3.2)
Heart murmurs77 (0.9)75 (0.9)
Palpitations1088 (12.6)1141 (13.2)
Collapse63 (0.7)76 (0.9)
Comorbidities (n, %)
 Hypertension3386 (39.2)3310 (38.4)
 Diabetes mellitus843 (9.8)686 (7.9)
 Dyslipidaemia2078 (24.1)1957 (22.7)
 Cardiovascular diagnosis at baseline1061 (12.3)939 (10.9)
Clinical characteristics
 Body mass index (kg/m2)27.0 (4.5)27.0 (4.7)
 Systolic blood pressure (mmHg)146 (21)146 (22)
 Total cholesterol (mmol/L)5.53 (1.29)5.62 (0.86)
 Low-density lipoprotein cholesterol (mmol/L)3.30 (2.50–4.20)3.30 (2.90–3.80)
 High-density lipoprotein cholesterol (mmol/L)1.40 (1.10–1.80)1.40 (1.10–1.80)
 Triglycerides (mmol/L)1.50 (1.00–2.20)1.50 (1.00–2.20)
 Estimated glomerular filtration rate (mL/min/1.73 m2)82 (27)82 (28)
 History of cardiovascular medication use970 (11.2)971 (11.3)
 Cardiovascular medication prescribed at baseline5798 (67.2)5807 (67.3)
No of cardiovascular medications
02256 (26.1)2240 (26.0)
1–35316 (61.6)5457 (63.2)
4–71048 (12.1)924 (10.7)
8–1011 (0.1)10 (0.1)
Blood pressure lowering medication5388 (62.4)5352 (62.0)
Antiplatelet or anticoagulant medication3086 (35.8)3032 (35.1)
Other lipid-lowering medication187 (2.2)191 (2.2)
Diabetes mellitus medication728 (8.4)572 (6.6)
Nitrates859 (10.0)803 (9.3)
Antiarrhythmic medication108 (1.3)121 (1.4)
Digoxin62 (0.7)65 (0.8)
Statin prescriptions at baseline (n, %)
Statin name
Atorvastatin1859 (21.5)
Fluvastatin42 (0.5)
Pravastatin643 (7.4)
Rosuvastatin889 (10.3)
Simvastatin5198 (60.2)
Statin intensity
Lower than guideline recommended2805 (32.5)
Equal to guideline recommended3473 (40.2)
Higher than guideline recommended2353 (27.3)
  • SCORE, Systematic COronary Risk Evaluation.