Table 4

HMR-level and haemodynamic characteristics

Low HMR (≤2.5) n=257High HMR (>2.5) n=199P value
Age65.5±9.969.0±9.5<0.001
Male/female204/53145/540.10
HTN/non-HTN158/97142/530.02
DM/non-DM65/19262/1360.16
FFR0.81±0.10.83±0.10.003
CFR2.3±0.62.0±0.5<0.001
DS%63.3±1263.6±140.85
Pd/Pa0.92±0.10.93±0.10.035
HMR mm Hg/cm/s1.8±0.43.3±0.8<0.001
HSR mm Hg/cm/s0.47±0.40.72±0.7<0.001
bAPV cm/s20.6±8.313.4±3.8<0.001
hAPV cm/s42.9±15.024.7±6.2<0.001
  • Per-vessel analysis of key haemodynamic parameters divided according to HMR (cut-off 2.5) Mean±SD. T-test adjusted for difference in variances. Categorical variables analysed with Kruskal-Wallis H test.

  • bAPV, baseline average peak velocity; CFR, coronary flow reserve; DM, diabetes; DS, diameter stenosis; FFR, fractional flow reserve; hAPV, hyperemic average peak velocity; HMR, hyperemic microvascular resistance; HSR, hyperemic stenosis resistance; HTN, hypertension; LAD, left anterior descending artery; Pd/Pa, distal and aortic pressure.