Haemodynamic data according to FFR and CFR levels
| Concordant normal (A) | Discordant (B) | Concordant abnormal (C) | Reverse discordant (D) | P value | |
| FFR>0.80 and CFR≥2.0 | FFR≤0.80 and CFR≥2.0 | FFR≤0.80 and CFR<2.0 | FFR>0.80 and CFR<2.0 | ||
| n | 201 | 68 | 88 | 99 | |
| Male/female | 154/47 | 52/16 | 66/22 | 77/22 | 0.98 |
| LAD/non-LAD | 130/71 | 53/15 | 59/29 | 50/49 | 0.003 |
| HTN/non-HTN | 132/66 | 40/28 | 56/30 | 72/26 | 0.43 |
| DM/non-DM | 49/151 | 19/49 | 33/55 | 26/73 | 0.15 |
| FFR | 0.88±0.05 | 0.74±0.04* | 0.68±0.10* | 0.88±0.05 | <0.001 |
| CFR | 2.5±0.4 | 2.6±0.3 | 1.5±0.3* | 1.7±0.2* | <0.001 |
| DS% | 57.6±11.0* | 64.0±10.6§ | 76.0±10.6 | 63.6±13.0 | <0.001 |
| Pd/Pa | 0.96±0.03 | 0.90±0.04* | 0.83±0.09* | 0.96±0.03 | <0.001 |
| HMR mm Hg/cm/s | 2.4±0.89† | 1.91±0.64* | 2.53±0.93 | 2.92±1.2 | <0.001 |
| HSR mm Hg/cm/s | 0.32±0.18† | 0.66±0.25* | 1.3±0.78* | 0.38±0.22 | <0.001 |
| bAPV cm/s | 15.8±6.3 | 16.3±6.5 | 20.0±8.5‡ | 19.1±9.1‡ | <0.001 |
| hAPV cm/s | 37.7±11.0 | 40.1±16.0 | 28.9±13.7‡ | 35.0±15.0‡ | <0.001 |
Per-vessel analysis of key haemodynamic parameters divided according to FFR (cut-off 0.80) and CFR (cut-off 2.0). Mean±SD.
Generalised estimated equation model with pairwise Bonferroni test. Categorical variables analysed with Kruskal-Wallis H test.
*<0.0001 versus all groups.
†<0.001 versus B and D.
‡<0.05 versus A and B.
§<0.05 versus A and C.
bAPV, baseline average peak velocity; CFR, coronary flow reserve; DM, diabetes; DS, Diameter stenosis; FFR, fractional flow reserve; hAPV, hyperemic average peak velocity; HMR, hyperemic microvascular resistance; HSR, hyperemic stenosis resistance; HTN, hypertension; LAD, left anterior descending artery; Pd/Pa, distal and aortic pressure.