All patients | No anticoagulation therapy | Anticoagulation therapy | P* | ||||
n=7174 | n=2338 (32.6%) | n=4809 (67.0%) | |||||
n | % | n | % | n | % | ||
Female | 2896 | 40.4 | 946 | 40.5 | 1940 | 40.3 | 0.94 |
Mean age (year (SD)) | 80 (10) | 80 (11) | 80 (9) | 0.13 | |||
Age <50 years | 43 | 0.6 | 19 | 0.8 | 22 | 0.5 | <0.001 |
Age 50–59 years | 178 | 2.5 | 72 | 3.1 | 104 | 2.2 | 0.02 |
Age 60–69 years | 848 | 11.7 | 302 | 12.9 | 533 | 11.1 | 0.02 |
Age 70–79 years | 2110 | 29.4 | 599 | 25.6 | 1504 | 31.3 | <0.001 |
Age≥80 years | 4005 | 55.8 | 1446 | 57.8 | 2646 | 55.0 | 0.04 |
Previous coronary heart disease | |||||||
Myocardial infarction | 2238 | 31.2 | 709 | 30.3 | 1524 | 31.7 | 0.24 |
Percutaneous coronary intervention | 1440 | 20.1 | 440 | 18.8 | 996 | 20.7 | 0.07 |
Coronary artery bypass grafting | 1079 | 15.0 | 286 | 12.3 | 789 | 16.4 | <0.001 |
Previous stroke (all types) | 1070 | 14.9 | 329 | 14.1 | 735 | 15.3 | 0.17 |
Smoking | 2724 | 38.0 | 839 | 35.9 | 1879 | 39.1 | 0.01 |
Previous antihypertensive treatment | 4353 | 10.7 | 1359 | 58.3 | 2976 | 61.9 | 0.003 |
Previous diabetes mellitus diagnosis | 1756 | 24.5 | 544 | 23.3 | 1205 | 25.1 | 0.1 |
Previous heart failure diagnosis | 1439 | 20.1 | 392 | 16.8 | 1039 | 21.6 | <0.001 |
Renal failure (eGFR <60 mL/min) | 3666 | 51.1 | 1290 | 52.1 | 2435 | 50.6 | 0.20 |
Type 1 myocardial infarction | 4810 | 67.1 | 1668 | 71.3 | 3125 | 65.0 | <0.001 |
Type 2 myocardial infarction | 2274 | 31.7 | 648 | 27.7 | 1616 | 33.6 | <0.001 |
ST-elevation myocardial infarction | 957 | 13.3 | 372 | 15.9 | 580 | 12.1 | <0.001 |
Coronary angiography | 3198 | 44.6 | 990 | 42.3 | 2199 | 45.7 | 0.01 |
Percutaneous coronary intervention | 1998 | 27.9 | 655 | 28.0 | 1336 | 27.8 | 0.96 |
Mean CHA2DS2-VASc risk score at discharge (SD) | 4.4 (1.4) | 4.3 (1.4) | 4.5 (1.4) | <0.001 |
P*=comparison of anticoagulated and non-anticoagulated patients.
CHA2DS2-VASc, congestive heart failure, hypertension, age ≥75 (doubled), diabetes, stroke (doubled), vascular disease, age 65–75, and sex (female); eGFR, estimated glomerular filtration rate.