All-cause mortality: univariate and multivariable Cox regression analysis
| Variable | Univariate HR (95% CI) | P value | Multivariate HR (95% CI) | P value |
| Severe atrial dilation | 1.36 (1.11 to 1.67) | 0.003 | 1.26 (1.01 to1.57) | 0.04 |
| ≥moderate RV dilation | 1.32 (1.11 to 1.58) | 0.002 | 1.15 (0.95 to 1.39) | 0.15 |
| ≥moderate RV dysfunction | 1.13 (0.94 to 1.36) | 0.19 | N/A | N/A |
| TAPSE | 0.93 (0.72 to 1.20) | 0.93 | N/A | N/A |
| ≥2+ TR | 1.48 (1.22 to 1.78) | <0.001 | 0.16 (0.94 to 1.44) | 0.17 |
| SPAP | 1.02 (1.01 to 1.02) | <0.001 | 1.01 (1.00 to 1.02) | 0.002 |
| EROA | 1.00 (0.99 to 1.01) | 0.4 | N/A | N/A |
| LVEF | 1.00 (0.99 to 1.01) | 0.98 | N/A | N/A |
| LV end-diastolic volume | 0.99 (0.99 to 1.00) | 0.31 | N/A | N/A |
| LV end-systolic volume | 0.99 (0.99 to 1.00) | 0.36 | N/A | N/A |
| Age | 1.03 (1.02 to 1.04) | <0.001 | 1.03 (1.02 to 1.04) | <0.001 |
| Female sex | 0.79 (0.67 to 0.95) | 0.01 | 0.85 (0.71 to 1.03) | 0.09 |
Significant p-values (<0.05) are highlighted in bold.
EROA, effective regurgitant orifice area; LV, left ventricle; LVEF, left ventricular ejection fraction; N/A, not available; RV, right ventricle; SPAP, systolic pulmonary arterial pressure; TAPSE, Tricuspid Annular Plane Systolic Excursion; TR, tricuspid regurgitation.