List of maternal HDs included in class X
| Maternal HDs included in class X* | N=38 pregnancies |
| Mild LV hypertrophy (no LV impairment) | 1 (2.6) |
| Moderate LV hypertrophy (no LV impairment) | 14 (36.8) |
| Pericardial effusion/pericarditis | 5 (13.2) |
| Previous myocarditis (no sequelae) | 1 (2.6) |
| Previous myocardial infarction (no LV impairment)† | 5 (13.2) |
| Previous trivasal coronaropathy requiring coronary artery bypass graft | 1 (2.6) |
| Previous massive pulmonary embolism with cardiac arrest and hypoxic encephalopathy | 1 (2.6) |
| Left-sided superior vena cava with coronary sinus dilation | 1 (2.6) |
| Previous PSVT with acute pulmonary oedema and mildly elevated PAP‡ | 2 (5.3) |
| Atrioventricular block with PPM | 3 (7.9) |
| Brugada syndrome with ICD | 2 (5.3) |
| Sino-atrial node disease with PPM | 1 (2.6) |
| Cardiovascular event without history of HD§ | 3 (7.9) |
Data shown as number (%).
*Sum of pregnancies in each category exceeds total (n=40) due to presence of patients with more than one diagnosis. For these patients, the HD with the highest potential for complications was considered for classification.
†This group includes: myocardial infarction with non-obstructive coronary arteries (n=1), ventricular fibrillation with cardiac arrest and myocardial infarction with non-obstructive coronary arteries (n=3), myocardial infarction with recurrent pericarditis (n=1).
‡This is a patient with two pregnancies during the study period, in 2013 and 2015. In 2009, during her first pregnancy, she underwent a caesarean section for failure to progress at complete dilation; surgery was complicated by an episode of paroxysmal supraventricular tachycardia responsive to pharmacological treatment. Three hours after delivery, acute pulmonary oedema was diagnosed, which required admission to the intensive care unit for 36 hours. Mildly elevated pulmonary arterial pressure was identified, which resolved a few days after the acute event.
§This group includes: myocardial infarction with congestive heart failure (n=1), myocardial infarction with non-obstructive coronary arteries (n=1), hypokinetic cardiomiopathy with congestive heart failure (n=1). All these women displayed risk factors for CVD, including maternal age >40 years (n=2), pregestational BMI >35 kg/m2 (n=1), chronic hypertension (n=2) and cigarette smoking (n=3).
BMI, body mass index ; CVD, cardiovascular disease; HD, heart disease; ICD, implantable cardioverter defibrillator; LV, left ventricle; PAP, pulmonary arterial pressure; PPM, permanent pacemaker; PSVT, paroxysmal supraventricular tachycardia.