Table 3

Comparison of CMR parameters across groups

Entire cohortPH groupP value
N=52No PH
(n=5)
Pre-capillary PH (n=3)IPC-PH
(n=29)
CpcPH
(n=15)
Indexed LV mass (gm/m2)115.7±29.4105.5±52.9124.9±14.1117.0±27.7114.8±26.80.79
Max wall thickness (mm)18.7±4.518.2±6.117.0±6.119.1±4.618.3±4.00.92
LVEDVI (mL/m2)72.5 (62.9–86.2)60.2 (46.9–95.0)72.0 (70.5–92.2)75.8 (65.5–90.1)69.3 (61.3–73.8)0.24
LVESVI (mL/m2)40.7 (32.9–50.4)24.4 (20.6–45.5)47.3 (44.8–56.8)41.3 (33.3–51.3)40.0 (36.3–48.3)0.13
LVEF (%)43.0±12.953.9±17.035.4±17.642.6±11.941.7±11.80.54
RVEDVI (mL/m2)76.1 (65.3–98.4)86.7 (48.2–92.7)110.0 (103.8–117.3)76.0 (66.4–96.0)73.5 (62.0–89.7)0.11
RVESVI (mL/m2)47.0 (34.5–60.5)32.8 (26.0–51.9)75.5 (65.8–82.6)43.6 (37.5–57.7)51.4 (35.0–60.1)0.07
RVEF (%)40.5±11.949.6±10.231.9±15.641.2±11.037.9±12.40.28
Indexed LA volume (mL/m2)67.6±15.458.4±20.386.5±7.770.2±13.062.1±15.40.02
Native T1 (msec)1109±711113±401090±141111±771108±790.53
ECV (%)53.9±11.548.4±9.060.7±12.653.0±11.556.4±12.20.47
Peak radial LV strain (%)15.6 (10.5–18.7)18.2 (11.6–26.7)15.7 (13.7–16.4)16.6 (10.3–20.9)13.7 (10.8–16.8)0.52
Peak circumferential LV strain (%)−11.2 (−15.9–−8.3)−12.0 (−16.2–−9.0)−11.5 (−11.7–−10.1)−12.0 (−13.8–−8.3)−10.3 (−12.1–−8.5)0.58
Peak LV longitudinal strain (%)−6.8 (−8.9–−5.4)−6.7 (−6.8–−6.4)−7.4 (−8.2–−5.8)−6.9 (−9.5–−5.2)−7.2 (−8.5–−5.6)0.99
Peak RV radial strain (%)10.6 (7.6–14.2)17.3 (4.4–30.1)13.9 (6.3–21.6)10.9 (8.4–15.0)9.6 (7.0–10.7)0.55
Peak RV circumferential strain (%)−7.9 (−10.0–−5.9)−10.4 (−17.2–−3.6)−9.1 (−13.2–−5.0)−8.2 (−10.8–−6.1)−6.9 (−8.3–−5.9)0.61
Peak RV longitudinal strain (%)−12.9 (−16.5–−10.2)−16.2±7.2−13.0±5.2−14.5±5.4−12.6±3.40.59
Indexed LV mass (gm/m2)115.7±29.4105.5±52.9124.9±14.1117.0±27.7114.8±26.80.79
Max wall thickness (mm)18.7±4.518.2±6.117.0±6.119.1±4.618.3±4.00.92
LVEDVI (mL/m2)72.5 (62.9–86.2)60.2 (46.9–95.0)72.0 (70.5–92.2)75.8 (65.5–90.1)69.3 (61.3–73.8)0.24
LVESVI (mL/m2)40.7 (32.9–50.4)24.4 (20.6–45.5)47.3 (44.8–56.8)41.3 (33.3–51.3)40.0 (36.3–48.3)0.13
LVEF (%)43.0±12.953.9±17.035.4±17.642.6±11.941.7±11.80.54
RVEDVI (mL/m2)76.1 (65.3–98.4)86.7 (48.2–92.7)110.0 (103.8–117.3)76.0 (66.4–96.0)73.5 (62.0–89.7)0.11
RVESVI (mL/m2)47.0 (34.5–60.5)32.8 (26.0–51.9)75.5 (65.8–82.6)43.6 (37.5–57.7)51.4 (35.0–60.1)0.07
RVEF (%)40.5±11.949.6±10.231.9±15.641.2±11.037.9±12.40.28
Indexed LA volume (mL/m2)67.6±15.458.4±20.386.5±7.770.2±13.062.1±15.40.02
Native T1 (msec)1109±711113±401090±141111±771108±790.53
ECV (%)53.9±11.548.4±9.060.7±12.653.0±11.556.4±12.20.47
Peak radial LV strain (%)15.6 (10.5–18.7)18.2 (11.6–26.7)15.7 (13.7–16.4)16.6 (10.3–20.9)13.7 (10.8–16.8)0.52
Peak circumferential LV strain (%)−11.2 (−15.9–−8.3)−12.0 (−16.2–−9.0)−11.5 (−11.7–−10.1)−12.0 (−13.8–−8.3)−10.3 (−12.1–−8.5)0.58
Peak LV longitudinal strain (%)−6.8 (−8.9–−5.4)−6.7 (−6.8–−6.4)−7.4 (−8.2–−5.8)−6.9 (−9.5–−5.2)−7.2 (−8.5–−5.6)0.99
Peak RV radial strain (%)10.6 (7.6–14.2)17.3 (4.4–30.1)13.9 (6.3–21.6)10.9 (8.4–15.0)9.6 (7.0–10.7)0.55
Peak RV circumferential strain (%)−7.9 (−10.0–−5.9)−10.4 (−17.2–−3.6)−9.1 (−13.2–−5.0)−8.2 (−10.8–−6.1)−6.9 (−8.3–−5.9)0.61
Peak RV longitudinal strain (%)−12.9 (−16.5–−10.2)−16.2±7.2−13.0±5.2−14.5±5.4−12.6±3.40.59
  • CpcPH, combined post and pre-capillary PH; ECV, extracellular vol; EDVI, Indexed end diastolic volume; EF, ejection fraction; ESVI, indexed end systolic volume; IPC-PH, isolated post-capillary PH; IPC-PH, isolated post-capillary PH; LA, left atrium; LV, left ventricle; PH, pulmonary hypertension; RV, right ventricle.