Table 4

Multivariable linear regression for prediction of right ventricular function

TAPSE (cm)RV-s' (cm/s)RVFWS (%)
UnivariableMultivariable
(n=99, r2=0.36)
UnivariableMultivariable
(n=98, r2=0.36)
UnivariableMultivariable
(n=93, r2=0.30)
β95% CIP valueβ95% CIP valueβ95% CIP valueβ95% CIP valueβ95% CIP valueβ95% CIP value
Gender (reference=female)0.37−0.01 to 0.760.0560.500.14 to 0.850.0070.730.36 to 1.11<0.0010.730.38 to 1.08<0.0010.32−0.06 to 0.710.1010.31−0.04 to 0.660.084
Age at examination (years)0.14−0.06 to 0.340.1610.08−0.12 to 0.270.447−0.00−0.20 to 0.200.984−0.17−0.37 to 0.020.0790.06−0.14 to 0.250.5670.19−0.00 to 0.380.053
Body mass index (kg/m2)0.19−0.01 to 0.380.0560.14−0.8 to 0.350.2080.250.06 to 0.440.0110.210.00 to 0.430.048−0.10−0.32 to 0.120.383−0.28−0.50 to −0.050.017
Heart rate (bpm)−0.25−0.44 to −0.060.011−0.09−0.28 to 0.100.3350.03−0.17 to 0.230.7820.14−0.05 to 0.320.1430.15−0.04 to 0.340.1210.01−0.17 to 0.200.885
Anthracyclines dosage (mg/m2)−0.11−0.30 to 0.090.2700.07−0.12 to 0.260.451−0.23−0.42 to −0.030.022−0.02−0.20 to 0.160.857−0.14−0.05 to 0.330.1490.05−0.14 to 0.230.620
Hypertension−0.07−0.41 to 0.390.9740.10−0.30 to 0.510.6100.12−0.28 to 0.520.556
Hypercholesterolaemia−0.32−0.88 to 0.230.250−0.19−0.74 to 0.370.5030.20−0.38 to 0.780.501
GVHD (including BOS)−0.36−0.76 to 0.050.081−0.34−0.72 to 0.050.085−0.25−0.66 to 0.160.222−0.28−0.65 to 0.100.147−0.03−0.44 to 0.380.900−0.15−0.54 to 0.230.430
GLS (%)−0.44−0.62 to −0.26<0.001−0.48−0.67 to −0.29<0.001−0.27−0.45 to −0.080.006−0.43−0.62 to −0.24<0.0010.450.27 to 0.62<0.0010.410.23 to 0.60<0.001
2D-LVEF (%)0.320.13 to 0.500.0010.280.09 to 0.470.004−0.24−0.42 to −0.050.011
E/e'0.08−0.12 to 0.270.4310.14−0.06 to 0.340.1580.190.00 to 0.380.048−0.12−0.33 to 0.080.232
PASP (mm Hg)0.15−0.05 to 0.340.1330.18−0.05 to 0.290.1770.13−0.07 to 0.320.1910.04−0.13 to 0.210.659−0.04−0.23 to 0.150.675
  • All continuous variables are standardised. GLS and RVFW are entered as negative values. Statistically significant values in boldface (p<0.05).

  • BOS, bronchiolitis obliterans syndrome; 2D, two dimensions; E/e', ratio of early-diastolic velocity to mean early-diastolic myocardial velocity; GLS, global longitudinal strain; GVHD, graft-versus-host disease; LVEF, left ventricular ejection fraction; PASP, pulmonary arterial systolic pressure; RV-e', RV early-diastolic velocity; RVFWS, RV-free-wall strain; RV-s', RV-peak systolic velocity; TAPSE, tricuspid annular plane systolic excursion.