Concentrations of sST2 and other cardiovascular and inflammatory biomarkers measured at baseline in association with outcome (medical ward, intensive care unit (ICU) or non-survivor) among patients hospitalised with COVID-19 (n=123)
| Medical ward | ICU | Non-survivors | Medical ward versus ICU | Medical ward versus non-survivors | |||
| n=88 | n=27 | n=8 | Unadjusted | Adjusted* | Unadjusted | Adjusted* | |
| sST2 (ng/mL) | 43 (36, 59) | 67 (39, 104) | 107 (72, 116) | <0.001 | 0.001 | <0.001 | 0.03 |
| Interleukin-6 (pg/mL) | 30 (16, 55) | 63 (38, 106) | 109 (32, 186) | 0.023 | 0.09 | 0.02 | 0.35 |
| C reactive protein (mg/L) | 55 (27, 110) | 130 (49, 220) | 115 (75, 200) | 0.004 | 0.008 | 0.07 | 0.38 |
| Procalcitonin (µg/L) | 0.10 (0.06, 0.18) | 0.19 (0.11, 0.60) | 0.19 (0.14, 0.74) | 0.002 | 0.002 | 0.03 | 0.66 |
| Ferritin (µg/L) | 411 (194, 751) | 901 (353, 2744) | 1142 (434, 1853) | <0.001 | <0.001 | 0.02 | 0.13 |
| D-dimer (mg/L) | 0.5 (0.3, 0.8) | 0.7 (0.4, 0.9) | 1.05 (0.9, 2.4) | 0.83 | 0.97 | 0.04 | 0.71 |
| Cardiac troponin T (ng/L) | 8 (4, 15) | 9 (7, 14) | 25 (18, 30) | 0.75 | 0.26 | 0.02 | 0.08 |
| NT-proBNP (ng/L) | 90 (29, 259) | 130 (83, 188) | 359 (192, 1431) | 0.70 | 0.85 | 0.03 | 0.15 |
Concentrations are reported as median (Q1, Q3). All biomarker values were log-transformed in the adjusted regression models.
*Adjusted for: age, sex, race, body mass index, cardiovascular disease and estimated glomerular filtration rate at baseline.
sST2, soluble ST 2.