Baseline characteristics and vital parameters on admission in patients hospitalised for COVID-19, stratified by quartiles of baseline sST2 concentrations (n=123)
sST2 range (ng/mL) | sST2 Q1 | sST2 Q2 | sST2 Q3 | sST2 Q4 | P value for trend |
n=31 | n=31 | n=31 | n=30 | ||
22–37 | 38–48 | 49–67 | 67 ->200 | ||
Age, years | 54.9±14.4 | 57.5±15.4 | 59.0±16.5 | 67.3±11.6 | 0.002 |
Male sex, n (%) | 12 (38.7) | 17 (54.8) | 20 (64.5) | 23 (76.7) | 0.002 |
White race, n (%) | 16 (51.6) | 13 (41.9) | 16 (51.6) | 23 (76.7) | 0.037 |
Body mass index, kg/m2 | 28.6±6.3 | 28.0±5.2 | 29.5±6.5 | 27.1±3.1 | 0.49 |
Obesity, n (%) | 7 (22.6) | 9 (31.0) | 9 (30.0) | 7 (23.3) | 0.96 |
Diabetes mellitus, (%) | 3 (9.7) | 4 (12.9) | 4 (12.9) | 10 (33.3) | 0.021 |
Hypertension, (%) | 6 (19.4) | 7 (23.3) | 10 (32.3) | 16 (55.2) | 0.002 |
Cardiovascular disease, (%) | 3 (9.7) | 4 (12.9) | 4 (12.9) | 7 (23.3) | 0.16 |
Chronic kidney disease, n (%) | 1 (3.2) | 1 (3.2) | 0 (0.0) | 7 (23.3) | 0.007 |
Chronic pulmonary disease, n (%) | 1 (3.2) | 2 (6.5) | 1 (3.2) | 2 (6.7) | 0.69 |
Smoking, n (%) | 1 (3.2) | 0 (0.0) | 1 (3.2) | 4 (13.3) | 0.06 |
Days of symptoms | 10±5 | 9±5 | 9±4 | 9±4 | 0.52 |
Oxygen saturation, % | 94±3 | 94±3 | 93±2 | 89±9 | <0.001 |
Temperature, °C | 38.1±1.0 | 37.9±0.9 | 38.2±0.9 | 38.2±1.0 | 0.51 |
Heart rate, /min | 88±16 | 89±14 | 90±17 | 93±19 | 0.24 |
Respiratory rate, /min | 22±5 | 27±8 | 28±7 | 30±11 | <0.001 |
Systolic blood pressure, mm Hg | 130±13 | 135±19 | 133±23 | 130±19 | 0.86 |
Values are reported as number (proportions) or mean±SD.
sST2, soluble ST2.