Table 1

Baseline characteristics of SI and poor SI

SI (n=1633)Poor SI (n=116)P value
Age (years)85 (82–88)86 (82–89)0.055
Male472 (28.9%)30 (25.9%)0.48
BMI (kg/m2)22.1 (19.8–24.6)21.9 (19.5–24.3)0.66
DM338 (20.7%)29 (25.0%)0.27
DL713 (43.7%)48 (41.4%)0.63
HT1256 (76.9%)89 (76.7%)0.96
Hb11.3 (10.2–12.5)10.7 (9.6–11.9)0.001
Serum albumin ≤3.5 g/dL425 (26.0%)44 (37.9%)0.005
CKD (eGFR <60 mL/min/1.73 m2)1132 (69.3%)101 (87.1%)<0.001
COPD211 (12.9%)23 (19.8%)0.035
CFS ≥4912 (55.8%)89 (76.7%)<0.001
CAD559 (34.2%)49 (42.2%)0.080
PAD149 (9.1%)17 (14.7%)0.050
AF325 (19.9%)49 (42.2%)<0.001
BNP (pg/mL)247.7 (112.0–531.4)369.2 (160.8–604.7)0.005
LVEF (%)62.3 (52.5–68.2)59.9 (44.8–68.8)0.062
LFLG AS141 (8.9%)22 (19.5%)<0.001
E/e’19.5 (15.2–25.3)20.9 (16.1–28.8)0.065
Preprocedural moderate to severe AR177 (10.8%)11 (9.5%)0.65
Preprocedural moderate to severe MR167 (10.2%)30 (25.9%)<0.001
Preprocedural moderate to severe MS20 (1.3%)3 (2.7%)0.20
Preprocedural moderate to severe TR101 (6.2%)20 (17.2%)<0.001
STS-PROM (%)6.2 (4.4–8.8)7.8 (5.0–12.6)<0.001
  • Values are medians (25th–75th percentiles) or number (%).

  • AF, atrial fibrillation; AR, aortic regurgitation; BMI, body mass index; BNP, brain natriuretic peptide; CAD, coronary artery disease; CFS, Clinical Frailty Scale; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; DL, dyslipidaemia; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; Hb, haemoglobin; HT, hypertension; LFLG AS, low-flow low-gradient aortic stenosis; LVEF, left ventricular ejection fraction; MR, mitral regurgitation; MS, mitral stenosis; PAD, peripheral arterial disease; SI, symptomatic improvement; STS-PROM, Society of Thoracic Surgery predicted risk of mortality; TR, tricuspid regurgitation.