Within-group change in TASQ after TAVR or SAVR
TAVR | SAVR | |||||
n | Paired difference versus baseline (95% CI) | P value | n | Paired difference versus baseline (95% CI) | P value | |
TASQ overall summary | ||||||
Discharge | 130 | 8.2 (5.3 to 11.0) | <0.001 | 128 | −1.8 (−4.5 to 1.0) | 0.209 |
30 days | 124 | 16.9 (13.6 to 2.1) | <0.001 | 118 | 9.1 (5.4 to 12.7) | <0.001 |
3 months | 119 | 19.7 (16.4 to 23.0) | <0.001 | 121 | 14.6 (10.8 to 18.3) | <0.001 |
TASQ physical symptoms | ||||||
Discharge | 130 | 1.8 (1.3 to 2.2) | <0.001 | 129 | 0.3 (−0.1 to 0.7) | 0.132 |
30 days | 124 | 2.4 (1.9 to 2.9) | <0.001 | 119 | 1.6 (1.1 to 2.1) | <0.001 |
3 months | 119 | 2.8 (2.3 to 3.2) | <0.001 | 122 | 2.1 (1.6 to 2.7) | <0.001 |
TASQ physical limitations | ||||||
Discharge | 128 | 3.2 (2.9 to 4.2) | <0.001 | 127 | 0.1 (−1.0 to 1.1) | 0.917 |
30 days | 124 | 7.1 (6.1 to 8.2) | <0.001 | 119 | 3.9 (2.8 to 5.1) | <0.001 |
3 months | 119 | 8.1 (7.1 to 9.1) | <0.001 | 121 | 6.1 (4.9 to 7.3) | <0.001 |
TASQ emotional impact | ||||||
Discharge | 130 | 2.8 (1.3 to 4.2) | <0.001 | 127 | −0.1 (−1.5 to 1.4) | 0.920 |
30 days | 122 | 5.9 (4.2 to 7.5) | <0.001 | 119 | 3.8 (1.8 to 5.7) | <0.001 |
3 months | 119 | 7.2 (5.4 to 9.0) | <0.001 | 121 | 6.4 (4.5 to 8.3) | <0.001 |
TASQ social limitations | ||||||
Discharge | 127 | 0.6 (−0.02 to 1.2) | 0.058 | 125 | −1.9 (−2.7 to −1.2) | <0.001 |
30 days | 122 | 2.0 (1.4 to 2.7) | <0.001 | 119 | −0.2 (−1.0 to 0.5) | 0.516 |
3 months | 118 | 2.8 (2.1 to 3.4) | <0.001 | 122 | 0.9 (0.2 to 1.5) | 0.013 |
TASQ health expectations | ||||||
Discharge | 127 | −0.2 (−0.5 to 0.1) | 0.242 | 128 | −0.2 (−0.5 to 0.05) | 0.100 |
30 days | 123 | −0.8 (−1.1 to −0.4) | <0.001 | 118 | −0.3 (−0.6 to 0.1) | 0.120 |
3 months | 119 | −1.1 (−1.4 to −0.7) | <0.001 | 120 | −1.0 (−1.4 to −0.5) | <0.001 |
All questions were used for the total score. Missing values were replaced by the mean score at that follow-up time point, provided that the patient had responded to at least 50% of the questions for that subscale; otherwise, patient questionnaires were excluded.
SAVR, surgical aortic valve replacement; TASQ, Toronto Aortic Stenosis Quality of Life Questionnaire; TAVR, transcatheter aortic valve replacement.