Table 2

Within-group change in TASQ after TAVR or SAVR

TAVRSAVR
nPaired difference versus baseline (95% CI)P valuenPaired difference versus baseline (95% CI)P value
TASQ overall summary
 Discharge1308.2 (5.3 to 11.0)<0.001128−1.8 (−4.5 to 1.0)0.209
 30 days12416.9 (13.6 to 2.1)<0.0011189.1 (5.4 to 12.7)<0.001
 3 months11919.7 (16.4 to 23.0)<0.00112114.6 (10.8 to 18.3)<0.001
TASQ physical symptoms
 Discharge1301.8 (1.3 to 2.2)<0.0011290.3 (−0.1 to 0.7)0.132
 30 days1242.4 (1.9 to 2.9)<0.0011191.6 (1.1 to 2.1)<0.001
 3 months1192.8 (2.3 to 3.2)<0.0011222.1 (1.6 to 2.7)<0.001
TASQ physical limitations
 Discharge1283.2 (2.9 to 4.2)<0.0011270.1 (−1.0 to 1.1)0.917
 30 days1247.1 (6.1 to 8.2)<0.0011193.9 (2.8 to 5.1)<0.001
 3 months1198.1 (7.1 to 9.1)<0.0011216.1 (4.9 to 7.3)<0.001
TASQ emotional impact
 Discharge1302.8 (1.3 to 4.2)<0.001127−0.1 (−1.5 to 1.4)0.920
 30 days1225.9 (4.2 to 7.5)<0.0011193.8 (1.8 to 5.7)<0.001
 3 months1197.2 (5.4 to 9.0)<0.0011216.4 (4.5 to 8.3)<0.001
TASQ social limitations
 Discharge1270.6 (−0.02 to 1.2)0.058125−1.9 (−2.7 to −1.2)<0.001
 30 days1222.0 (1.4 to 2.7)<0.001119−0.2 (−1.0 to 0.5)0.516
 3 months1182.8 (2.1 to 3.4)<0.0011220.9 (0.2 to 1.5)0.013
TASQ health expectations
 Discharge127−0.2 (−0.5 to 0.1)0.242128−0.2 (−0.5 to 0.05)0.100
 30 days123−0.8 (−1.1 to −0.4)<0.001118−0.3 (−0.6 to 0.1)0.120
 3 months119−1.1 (−1.4 to −0.7)<0.001120−1.0 (−1.4 to −0.5)<0.001
  • All questions were used for the total score. Missing values were replaced by the mean score at that follow-up time point, provided that the patient had responded to at least 50% of the questions for that subscale; otherwise, patient questionnaires were excluded.

  • SAVR, surgical aortic valve replacement; TASQ, Toronto Aortic Stenosis Quality of Life Questionnaire; TAVR, transcatheter aortic valve replacement.