Comparison of baseline and follow-up parameters
| Parameter | Total | non-iASD | iASD | |||
| Mean change FU – baseline | P value | Mean change FU – baseline | P value | Mean change FU – Baseline | P value | |
| NYHA Class | −1.1±1.0 | <0.01 | −1.1±0.9 | <0.01 | −1.1±1.1 | <0.01 |
| LVEF (%) | −2.4±10.3 | 0.14 | −1.4±10.5 | 0.5 | −3.8±10.1 | 0.14 |
| LVEDd (mm) | −0.1±11.0 | 0.96 | 2.6±11.3 | 0.33 | −4.9±9.0 | 0.10 (0.05) |
| LVESd (mm) | 1.0±11.6 | 0.67 | 4.0±11.7 | 0.15 | −5.4±9.0 | 0.11 |
| IVSd (mm) | 0.5±2.8 | 0.35 | 0.3±3.2 | 0.67 | 0.7±2.3 | 0.3 |
| PWd (mm) | 0.8±3.2 | 0.2 | 0.1±2.7 | 0.87 | 1.8±3.9 | 0.13 |
| LA diameter (mm) | −1.0±7.4 | 0.41 | 0.5±7.7 | 0.79 | −2.7±6.9 | 0.13 |
| sPAP (mm Hg) | −5.3±21.1 | 0.14 | −0.4±23.3 | 0.94 | −10.2±18.0 | 0.03 (0.02) |
| Grade of MR | −2.3±0.7 | <0.01 | −2.2±0.7 | <0.01 | −2.4±0.6 | <0.01 |
| Grade of TR | −0.2±1.0 | 0.17 | −0.04±1.0 | 0.86 | −0.5±1.0 | 0.07 (0.04) |
| TAPSE (mm) | −0.5±4.6 | 0.48 | −0.1±4.3 | 0.91 | −1.2±4.9 | 0.3 |
Values are mean±SD, or number (%). P values in parentheses refer to one-sided testing. Bold p values indicate statistically significant results.
FU, follow-up; IVSd, septum diameter; LA, left atrium; LVEDd, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVESd, left ventricular end-systolic diameter; MR, mitral regurgitation; NYHA, New York Heart Association; PWd, posterior wall diameter; sPAP, systolic pulmonary artery pressure; TAPSE, tricuspid annular plane systolic excursion; TR, tricuspid regurgitation.