Standardised 90-day risks in relation to periods 2008–2018 versus 2002–2007 among the 2523 patients with acute myocarditis
| Outcome measure | 2008–2018 | 2002–2007 | P value |
| (n=1727) | (n=796) | ||
| All-cause mortality, risk (95% CI) | 5.7% (4.6% to 6.8%) | 6.8% (5.2% to 8.5%) | 0.23 |
| HF, risk (95% CI) | 10.5% (9.0% to 11.9%) | 9.4% (7.5% to 11.3%) | 0.37 |
| VT/VF/arrest, risk (95% CI) | 1.6% (1.0% to 2.2%) | 3.3% (2.0% to 4.5%) | 0.018 |
| ICD implantation, risk (95% CI) | 2.5% (1.7% to 3.3%) | 1.8% (0.9% to 2.7%) | 0.25 |
The reported absolute risks of the outcomes for patients with acute myocarditis diagnosed during 2008–2018 versus during 2002–2007 standardised to the age, sex and comorbidity distribution of all patients were derived from multivariable Cox regression. The following covariates were included in the models: patient age, sex, hypertension, diabetes, chronic obstructive pulmonary disease, prior myocardial infarction, prior ischaemic heart disease, percutaneous cardiac intervention, coronary artery bypass grafting, stroke, peripheral artery disease, atrial fibrillation or flutter, HF, prior ventricular VT/VF/arrest and chronic kidney disease.
HF, heart failure; ICD, implantable cardioverter-defibrillator; VF, ventricular fibrillation; VT, ventricular tachycardia.